Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (35): 5676-5680.doi: 10.3969/j.issn.2095-4344.2014.35.018

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Bone cement kyphoplasty for repair of rheumatoid arthritis combined with Kümmell’s disease: a follow-up addressing vertebral height and spinal stabilization

Wang Jing-liang, Pi An-ping, Xin Zhi-qiang, Yu Bao-xin, Wang Jian-wen, Ye Yong-liang, Pan Meng,Zheng Quan-xin   

  1. Second Ward, Department of Spine Surgery, Guangzhou Orthopedic Hospital, Guangzhou 510049, Guangdong Province, China
  • Revised:2014-07-29 Online:2014-08-27 Published:2014-08-27
  • About author:Wang Jing-liang, M.D., Attending physician, Second Ward, Department of Spine Surgery, Guangzhou Orthopedic Hospital, Guangzhou 510049, Guangdong Province, China
  • Supported by:

    the Science and Technology Project of Yuexiu District of Guangzhou City, No. 2013-ws-004

Abstract:

BACKGROUND: For patients with rheumatoid arthritis and Kümmell’s disease, how to effectively control back pain, to recover patient’s locomotor activity and to avoid a vicious cycle of disuse osteoporosis is a key therapeutic target. Kyphoplasty is a recently developed new technology of minimally invasive spine surgery. Few reports concerned the kyphoplasty for rheumatoid arthritis and Kümmell’s disease.
OBJECTIVE: To assess the clinical outcome of bone cement kyphoplasty for the treatment of Kümmell’s disease combined with rheumatoid arthritis.
METHODS: From June 2012 to July 2013, 11 female patients at the age of 65.4±5.1 years with Kümmell’s disease combined with rheumatoid arthritis, who suffered from severe back pain, were treated with bone cement vertebroplasty. Back pain and imaging indexes were compared and observed before surgery and during follow-up. Imaging indexes contained preoperative and postoperative anterior height of vertebral body after fractures, the ratio of anterior height to posterior height of the vertebral body, and local kyphosis angle (Cobb method).
RESULTS AND CONCLUSION: No patients were lost to follow up. 11 patients were followed up for 6 to 12 months. Significant differences in follow-up and preoperative Visual Analogue Scale scores, anterior height of vertebral body after fractures, the ratio of anterior height to posterior height of the vertebral body, and local kyphosis angle were detected (P < 0.05). Two patients experienced bone cement leakage. No severe complications appeared such as pulmonary embolism or neurological dysfunction. These data confirmed that bone cement vertebroplasty for rheumatoid arthritis combined with Kümmell’s disease can effectively lessen back pain, partially restore the height of vertebral body after fracture, rebuild spinal stabilization, reduce local kyphosis, and is a safe effective repair method.


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


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Key words: vertebroplasty, thoracic vertebrae, lumbar vertebrae, fractures, ununited

CLC Number: