Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (2): 322-328.doi: 10.3969/j.issn.2095-4344.2014.02.026

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Outcomes of negative pressure wound therapy versus conventional dressing change in repair of wound on the body surface

Bai Ming, Zhao Ru, Wang Zhi, Long Xiao, Zeng Ang, Zhang Hai-lin, Wang Xiao-jun   

  1. Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2013-11-09 Online:2014-01-08 Published:2014-01-08
  • Contact: Wang Xiao-jun, M.D., Chief physician, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • About author:Bai Ming, M.D., Attending physician, Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Abstract:

BACKGROUND: Negative pressure wound therapy has been extensively used, but most people only knew the superiority of negative pressure wound therapy based on clinical experiences or subjective judgment.
OBJECTIVE: To observe the effects of negative pressure wound therapy on the wound on the body surface, and to compare with contemporaneous conventional method.
METHODS: A total of 45 patients with wound on the body surface treated in the Peking Union Medical College Hospital from January 2006 to December 2011 were enrolled in this study, including 25 patients undergoing negative pressure wound therapy and 20 patients undergoing conventional change dressing method. All clinical data were recorded.
RESULTS AND CONCLUSION: Negative pressure wound therapy was better than conventional method (P < 0.05), on terms of preoperative preparation period, wound granulation, bacterial scavenging, labor intensity of working staff and incidence of postoperative complications. However, no significant difference in therapy cost was detectable (P > 0.05). These results suggested that compared with conventional method, negative pressure wound therapy positively contributed to the healing, obviously shortened preoperative preparation, accelerated the diminution of wound, decreased the incidence of complications of reconstruction, lessened patient’s distress, reduced their economic cost, and diminished labor intensity of working staff. Negative pressure wound therapy has been proven an excellent tool of to promote wound healing.



中国组织工程研究
杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程


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Key words: negative pressure wound therapy, skin ulcer, wound infection, treatment outcome

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