Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (42): 7877-7880.doi: 10.3969/j.issn.1673-8225.2011.42.021

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Fabrication and characterization of chitosan/mesoporous bioactive glasses porous films

Jia Tian-bao1, Chen Jian-yong1, Feng Xin-xing1, 2, Chang Jiang2   

  1. 1Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou  310018, Zhejiang Province, China
    2Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai  200050, China
  • Received:2011-04-06 Revised:2011-06-15 Online:2011-10-15 Published:2011-10-15
  • Contact: Feng Xin-xing, Doctor, Associate professor, Master’s supervisor, Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou 310018, Zhejiang Province, China; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China fengxx@zstu.edu.cn
  • About author:Jia Tian-bao★, Studying for master’s degree, Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou 310018, Zhejiang Province, China jiatianbao_01@ 126.com
  • Supported by:

    the National Natural Science Foundation of China, No. 50973096*, 50903073*, 31070867*; Commonweal Project of Science and Technology Department of Zhejiang Province, No. 2010C31038*

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Abstract:

BACKGROUND: Chitosan (CS) and mesoporous bioactive glasses (MBG) have some good properties, such as biocompatibility and hemostasis, but the hemostatic effect of CS is limited and it is inconvenient to use the MBG directly.
OBJECTIVE: To prepare CS/MBG porous films
METHODS: CS and MBG porous film was prepared through a freeze drying process. The prepared porous films were characterized by using Fourier transform infrared spectroscopy, scanning electron microscope and X-ray diffraction. In addition, water adsorption, swelling ratio, the porosity and the mechanical property of the porous films were also studied.
RESLUTS AND CONCLUSION: CS/MBG could be blended homogeneously via the lyophilization. The hole of the porous films was relatively uniform. The porous films showed good water adsorption character, which could be modulated by varying the weight ratio of CS and MBG. The prepared porous films had a higher porosity. The composite films can be potentially applied as a wound dressing material.

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