Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (23): 4359-4366.doi: 10.3969/j.issn.1673-8225.2012.23.034

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Hematopoietic stem cell transplantation for treating hematological malignancies

Wu Bi-jia, Gong Jun-mei, Guo Tian-jian, Chen Wan-hong, Li Na   

  1. Department of Internal Medicine, the 421 Hospital of Chinese PLA, Guangzhou 510310, Guangdong Province, China
  • Received:2012-01-10 Revised:2012-05-06 Online:2012-06-03 Published:2013-11-06
  • About author:Wu Bi-jia, Chief physician, Department of Internal Medicine, the 421 Hospital of Chinese PLA, Guangzhou 510310, Guangdong Province, China wbj.88258855@163.com

Abstract:

BACKGROUND: In recent years, with the continuous development of hematology and related fields of basic and clinical research, hematopoietic stem cell transplantation has become an effective means of treatment for hematologic malignancies, or even the only way to cure certain blood diseases.
OBJECTIVE: According to the literature retrieval results, to comparatively analyze the literatures on the hematopoietic stem cell transplantation for treating hematological malignancies in SCI database and to explore the future development tendency of hematopoietic stem cell transplantation for treating hematological malignancies.
METHODS: A retrieval was performed for the literature of the hematopoietic stem cell transplantation for treating hematological malignancies, using key words of “hematopoietic stem cell, transplantation, acute myelogenous leukemia, non-hodgkin lymphoma, chronic myelocytic leukemia” between 2001-01 and 2010-12 in SCI database. The retrieval results were analyzed, and the trends were described in words and graphics.
RESULTS AND CONCLUSION: The overall literatures of the hematopoietic stem cell transplantation for treating hematological malignancies had an upward trend from 2001 to 2010. United States published more literature than other countries, which play an important role in the field of the hematopoietic stem cell transplantation for treating hematological malignancies. Most of literatures were published from Fred Hutchinson Cancer Research Center. This paper provides a valuable reference for researchers to understand the overview and present situation of this field.

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