Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (47): 8909-8915.doi: 10.3969/j.issn.1673-8225.2010.47.042

Previous Articles     Next Articles

Application of polypyrrole-based biomaterials in tissue engineering

Fan Jian-ping, Xie Ai-ni, Liu Cheng-gui, Zhang Kai-lun   

  1. Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan  430022, Hubei Province, China
  • Online:2010-11-19 Published:2010-11-19
  • Contact: Zhang Kai-lun, Professor, Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China Prozkl@yahoo.com.cn
  • About author:Fan Jian-ping★, Master, Department of Cardiovascular Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
  • Supported by:

    the National High Technology Research and Development Program of China (863 Program), No. 2007AA027Z439*

PDF

718

Abstract:

BACKGROUND: Polypyrrole (PPy) has been widely applied in biomedical fields due to its special electronic property. Past 20 years, there are an increasing number of studies on the application of PPy as a potentially electrically addressable tissue/cell support substrate for tissue/cell regeneration.
OBJECTIVE: To overall review the application of PPy in tissue engineering field, and to provide a new approach for the research and development of medical biomaterials.
METHODS: Pubmed and Chinese biomedicine literature database were searched using key word of “polypyrrole” for documents published between 1990 and 2010. Literatures related to application of PPy in tissue engineering field were included, and the repetitive articles were excluded.
RESULTS AND CONCLUSION: Totally 762 papers were searched by computer, according to the inclusive and exclusive criteria, 51 literature were reviewed. Currently, PPy has been widely used in the fields of cardiovascular tissue engineering, bone and muscle tissue engineering, as well as skin tissue engineering. Application of PPy and PPy-based biomaterials hold great potential in development of novel biomedical materials applied in tissue engineering due to their versatile functionality and superior biocompatibility.

CLC Number: