Chinese Journal of Tissue Engineering Research ›› 2026, Vol. 30 ›› Issue (23): 6040-6050.doi: 10.12307/2026.312

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Osteoporotic vertebral compression fractures: a visual analysis of current status and emerging trends

Qu Bolin1, Ciren Lunzhu2, Guo Jinyang1, 3, Meng Hanlu4, Ding Guanxiang1, 5, Sang Hongpeng1   

  1. 1Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China; 2Shannan People's Hospital, Shannan 856000, Tibet Autonomous Region, China; 3Inner Mongolia Minzu University, Tongliao 028000, Inner Mongolia Autonomous Region, China; 4Tongliao People’s Hospital, Tongliao 028000, Inner Mongolia Autonomous Region, China; 5Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou 014000, Inner Mongolia Autonomous Region, China
  • Received:2025-04-22 Accepted:2025-06-05 Online:2026-08-18 Published:2025-12-31
  • Contact: Sang Hongpeng, Chief physician, Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China
  • About author:Qu Bolin, MS, Attending physician, Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China
  • Supported by:
    Shannan Science and Technology Program Project, No. SNSBJKJJHXM2023015 (to CL); Public Hospital Scientific Research Joint Fund Project of Inner Mongolia Academy of Medical Sciences, No. 2024GLLH1015 (to SHP); Chifeng Natural Science Research Project, No. SZR2022144 (to SHP)

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Abstract: BACKGROUND: Current literature primarily focuses on comparing the clinical efficacy and surgical safety of various operative approaches for osteoporotic vertebral compression fractures, while there is a notable lack of research addressing the current status, hotspots, and future trends in the treatment and prognosis of osteoporotic vertebral compression fractures.
OBJECTIVE: To analyze the current status, hotspots and trends of research on osteoporotic vertebral compression fractures by bibliometric methods.
METHODS: English articles related to the treatment and prognosis of osteoporotic vertebral compression fractures published between 1994 and 2023 were retrieved from the Web of Science Core Collection. Bibliometric and visualization analyses were conducted using CiteSpace and VOSviewer to evaluate publication volume, geographic distribution, institutional contributions, journal rankings, author productivity, keyword co-occurrence, research hotspots, and citation impact, thereby exploring the hotspots and trends of research on osteoporotic vertebral compression fractures.
RESULTS AND CONCLUSION: A total of 2 275 publications were analyzed. Global research output of osteoporotic vertebral compression fractures demonstrated a steady upward trajectory, peaking in 2022 with 215 publications. Contributions spanned 68 countries/regions, with China leading in productivity (644 publications). Soochow University emerged as the most prolific institution (90 publications). European Spine Journal ranked first in publication volume (n=146), while Spine exhibited the highest citation count (n=1 923), citations per article (58.5), and H-index (45), ranked second in publication volume (n=106). Yang Huilin (China) was the most productive author (n=65), whereas Galibert P (France) received the highest citation count (n=300). Research themes evolved dynamically: early-stage focus centered on “vertebroplasty,” “balloon kyphoplasty,” and “polymethylmethacrylate (PMMA)”; mid-term shifts emphasized “surgical management” and “nonoperative treatment”; and recent expansion prioritized “safety” and “risk factors,” which will continue to gain sustained attention as a trend for future research.


Key words: bibliometrics, visual analysis, osteoporotic vertebral compression fractures, treatment, prognosis, VOSviewer, CiteSpace

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