Chinese Journal of Tissue Engineering Research ›› 2016, Vol. 20 ›› Issue (27): 3957-3962.doi: 10.3969/j.issn.2095-4344.2016.27.001

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Influence of sand therapy in Uyghur medicine on mechanical properties of rabbits’ femur based on three-dimensional finite element modeling

Li Yan-na1, Julaiti•Maitirouzi1, Nijiati•Waili1, Huang Shao-jun1, Dilina•Mahemuti1, Muhetaer•Kelimu1, Zhang Rui2   

  1. 1College of Mechanical Engineering, Xinjiang University, Urumqi 830047, Xinjiang Uygur Autonomous Region, China
    2CT Room, Image Center, the Sixth Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Revised:2016-04-20 Online:2016-06-30 Published:2016-06-30
  • Contact: Julaiti?Maitirouzi, Master, Associate professor, College of Mechanical Engineering, Xinjiang University, Urumqi 830047, Xinjiang Uygur Autonomous Region, China
  • About author:Li Yan-na, Studying for master’s degree, College of Mechanical Engineering, Xinjiang University, Urumqi 830047, Xinjiang Uygur Autonomous Region, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81160542

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Abstract:

BACKGROUND: On the basis of modern design method and numerical simulation, studies can explore the action mechanisms of sand therapy in Uyghur medicine.
OBJECTIVE: To explore a kind of non-homogeneous and isotropic biological bone finite element modeling method based on CT value, and to study the influence of sand therapy in Uyghur medicine on the mechanical properties of rabbits’ femur.
METHODS: Eight adult New Zealand white rabbits were used to establish osteoarthritis models of right posterior femur with papain. These rabbits were divided into sand therapy group and control group. In the sand therapy group, after treatment with sand therapy in Uyghur medicine, rabbit femoral models were scanned with CT. The fault image data were imported into MIMICS software. 3D model of femur was generated. The meshing was done. The material properties were given. Three-point bending in the Ansys was simulated and solved. Simultaneously, the isolated three point bending tests were performed in all rabbit models. The corresponding deflection and the maximum stress values were obtained. Finally, the results obtained from the three-dimensional finite element modeling method were compared with the results obtained from the experiments.
RESULTS AND CONCLUSION: (1) The deflection and the maximum stress obtained by the three-point bending simulation analysis with the three-dimensional finite element model of the rabbits’ femur were well correlated with the data obtained from the experiments. (2) These results indicate that the finite element modeling method is consistent with the structural and material properties of bone, which can be used to analyze the stress and deformation of bones.

 

 中国组织工程研究杂志出版内容重点：肾移植；肝移植；移植；心脏移植；组织移植；皮肤移植；皮瓣移植；血管移植；器官移植；组织工程

Key words: Finite Element Analysis, Femur, Osteoarthritis, Tissue Engineering

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