Re-cognition of exercise-induced central and peripheral fatigue

doi:10.3969/j.issn.2095-4344.2015.42.023

Abstract

Abstract:

BACKGROUND: Animal exhaustion models are used mostly in exercise-induced fatigue research, in which complete exhaustion is confused with sports fatigue.

OBJECTIVE: By understanding of exercise-induced fatigue, understanding the mechanism of its occurrence, to grasp the reasonable and effective control measures, which to eliminate fatigue is very important for improving public health, improving sports performance and preventing sports injuries.

METHODS: A computer-based search of Medline, Embase, CBMdisc and CNKI was used for articles related to exercise-induced fatigue published from 1966 to 2014. The keywords were “exercise-induced fatigue, peripheral fatigue; central fatigue, exercise-induced fatigue” in English and Chinese, respectively. Finally, 49 articles were included in result analysis.

RESULTS AND CONCLUSION: The criteria and condition control of exercise-induced fatigue should be recognized. The mechanisms of peripheral fatigue and central fatigue are still unclear. The peripheral fatigue may locate in the neuromuscular junction, T system, sarcoplasmic reticulum, mitochondria and myocardial cell membrane with the corresponding material changes. During the exercise-induced central fatigue, there are corresponding changes in the neurotransmitters produced by the central nervous system, transfers quality and neural hormone.
中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

Key words: Fatigue, Central Nervous System, Dopamine

Tian Feng. Re-cognition of exercise-induced central and peripheral fatigue[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(42): 6849-6854.

Figures/Tables 1

References

[1] 刘庆山,姜慧,樊云彩. 躯体性疲劳机制研究的进展与思考[J].南京体育学院学报自然科学版,2003,2(1):11-16; 43.
[2] 王静,刘洪涛,马强,等.运动性中枢疲劳时大鼠脑乳酸和糖原含量的变化[J]. 中国运动医学杂志,2005,24(2):152-155.
[3] Westerblad H, allen DG. Changes of intracellular pH due to repetitive stimulation of single fibers from mouse skeletal muscle. J Physiol Lond.1992;(449):49-71.
[4] Edman KA. Changes in force and stiffness induced by fatigue and intracellular acidification in frog muscle fibers.J Physil Lond.1993;(424):133-149.
[5] Metzger JM.pH modulation of the kinetics of a casensitive cross-bridge state transition in mammalian single skeletal muscle fibers.J Physiol Lond.1990; (428):751-764.
[6] Bertocci LA, Fleckenstein JL, Antonio J. Human muscle fatigue after glycogen depletion: a 31P magnetic resonance study. J Appl Physiol.1992;73: 75-81.
[7] 田野.运动性疲劳的机理研究[M].北京:人民体育出版社,1997.
[8] Leppik JA, Aughey RJ, Medved I, et al.Prolonged exercise to fatigue in humans impairs skeletal muscle Na+-K+-ATPase activity, sarcoplasmic reticulum Ca2+ release, and Ca2+ uptake. J Appl Physiol.2004;97: 1414-1423.
[9] Gasser RN,Vaughan-Jones RD. Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle.J Physiol Lond.1990;431: 713-741.
[10] Gramolini A,Renaud JM. Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. Am J Physiol Cell Physiol.1997;272: C1936-C1946.
[11] Hodgkin AL,Horowicz P. The influence of potassium and chloride ions on the membrane potential of single muscle fibres. J Physiol Lond.1959;148: 127-160.
[12] Bickham DC. Extracellular K accumulation:a physiological tramework for fatigue cluring intense exercise.J Physiol. 2004;554(3):593.
[13] Van Lunteren E, Moyer M.. Effects of DAP on diaphragm force and fatigue, including fatigue due to neurotransmission failure. J Appl Physiol.1996;81(5): 2214-2220.
[14] Byrd S, Bode A, Klug G. Effect of exercise of varying duration on sarcoplasmic reticulum function. J Appl Physiol. 1989; 66(3):1383-1389.
[15] Favero TG. Sarcoplasmic reticulum Ca2+ release and muscle fatigue. J Appl Physiol.1999;87(2): 471-483.
[16] Germinario E,Esposito A,Megighian A,et al.Effects of modulators of sarcoplasmic Ca2+ release on the development of skeletal muscle fatigue. J Appl Physiol. 2004;96: 645-649.
[17] Allen DG, Westerblad H. Role of phosphate and calcium stores in muscle fatigue. J Physiol. 2001;536(3);657-665.
[18] Gyorke S. Effects of repeated tetanic stimulation on excitation contraction coupling in cut muscle fibres of the frog. J Physiol Lond. 1993;464: 699-710.
[19] Westerblad H, Lee JA, Lännergren J, Cellular mechanisms of fatigue in skeletal muscle.Am J Physiol.1991;261(Cell Physiol. 30): C195-C209.
[20] Guter TE,Pfeiffer DR. Mechanisms bu which mitochondria transport calcium.Am J Physiol.1990;258(5 Pt 1):C755-86
[21] Lew H,Pyke S, Quintanilha A. Changes in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats. FEBS Lett. 1985;185(2):262-266.
[22] Kretzschmar M, Muller D, Hubscher J,et al.Influence of aging, training and acute physical exercise on plasma glutathione and lipid peroxides in man. Int J Sports Med.1991;12(2): 218-222.
[23] Ríos E, Ma JJ, González A. The mechanical hypothesis of excitation contraction Coupling in skeletal muscle. J Muscle Res Cell Motil.1991;(12): 127-135.
[24] Newsholme EA, Blomstrand E.Branched-Chain Amino Acids and Central Fatigue. American Society for Nutrition J. Nutr. 2006;136:274S-276S.
[25] Eva Blomstrand.A Role for Branched-Chain Amino Acids in Reducing Central Fatigue . American Society for Nutrition J. Nutr. 2006;136:544S-547S.
[26] Davis JM, Alderson NL, Welsh RS. Serotonin and central nervous system fatigue: nutritional considerations.Am J Clin Nutr.2000;72(suppl):573S–578S.
[27] Decombaz J, Reinhardt P, Anantharaman K, et al. Biochemical changes in a 100 km run: free amino acids ,urea , and creatinine. Eur J Appl Physiol.1979; 41:61-72.
[28] Keast D, Arstein D, Harper W, et al. Depression of plasma glutamine after exercise stress and its possible influence on the immune system. Med J Aust. 1995; 162:15–18.
[29] 章江州.芳香族氨基酸对运动性疲劳的影响[J].中国运动医学杂志,1991,10(4):229.
[30] Kingsbury KJ, Kay L, Hjelm M. Contrasting plasma free amino acid patterns in elite athletes: association with fatigue and infection.Br J Sports Med. 1998;32:25-33.
[31] Nishigaki Y , Bonilla E, Shanske S,et al. Exercise-induced muscle ‘burning’ fatigue, and hyper-CKemia: mtDNA T10010C mutation in tRNAGly. American Academy of Neurology. 2002;58:1282-1285.
[32] Piacentini MF, Meeusen R, Buyse L,et al. Hormonal responses during prolonged exercise are influenced by a selective DA/NA reuptake inhibitor. Br J Sports Med. 2004;38:129-133.
[33] Baily SP,Davis JM,Ahlborn EN .Neuroendocrine and substrate responses toaltered brain 5-HT activity during prolonged exercise to fatigue.J Appl Physiol. 1993; 76(6):3006-3012.
[34] Tanaka M,Nakamura F,Mizokawa S. et al .Establishment and assessment of a rat model of fatigue.Neurosci Lett.2003; 352(3):159-162.
[35] Fitts RH. Cellular mechanisms of muscle fatigue. Physiol Rev. 1994;74: 49-94.
[36] Weir JP, Beck TW, Cramer JT,et al.Is fatigue all in your head? A critical review of the central governor model. Br J Sports Med. 2006;40(7):573-586; discussion 586.
[37] Amann M, Eldridge MW, Lovering AT,et al.Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humans. J Physiol.2006;575(3):937-952.
[38] Kent-Braun JA, Ng AV, Doyle JW, et al. Human skeletal muscle responses vary with age and gender during fatigue due to incremental isometric exercise. J Appl Physiol. 2002; 93:1813-1823.
[39] 张力为.心理学研究的七个方向:以运动性心理疲劳为例[J]. 体育科学,2010,30(10) :3-11.
[40] 李小华.运动疲劳与恢复的生理过程研究[J].福建体育科技, 2011,(4):30-31.
[41] 杨涛.合理营养补充,有效缓解运动疲劳[J].中国学校体育, 2013, (1):82.
[42] 户丽,张红林,图娅,等.近5年针灸推拿消除运动性疲劳研究进展[J]. 针灸临床杂志, 2012,28(1):69.
[43] 刘建宇,刘黎明,李广周,等.经穴推拿抗运动性疲劳的实验研究[J].中国体育科技,2012,48(1):141-144.
[44] 邓嘉. 田径运动训练中运动性疲劳与恢复理论的研究[J]. 科技资讯,2011,(10):220-221.
[45] 孙国晓,张力为. 自我决定动机影响运动员心理疲劳:横向与纵向研究的证据[J]. 体育科学,2013,33(7):21-28.
[46] 刘方琳,张力为. 运动员心理疲劳的定性探索[J].体育科学,2004, 24(11):37-44.
[47] 金湖,吴家舵.关于运动性心理疲劳的研究概况[J].体育科研, 2006, 26(3):36-38.
[48] 赵茜,张力为.教练员心理疲劳的特征及相关因素[J].体育科学, 2007,27(12):38-39.