Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (22): 3457-3461.doi: 10.3969/j.issn.2095-4344.2015.22.003

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Ice intervention inhibits hemoglobin decrease and pain after total knee replacement

Xu Fei1, Lv Yong-ming1, Song Ying-chun1, Li Xia1, Xing En-hong1, Yang Yang1, Du Yuan-liang1, Zhang Li-chao1, Dai Hai-feng1, Dong Xiao-qiang2, He Wen-jing3, Zhang Yan-bo3   

  1. 1Third Department of Orthopedics, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China; 2Department of Orthopedics, ChengGang Branch, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China; 3Endoscopy Room, Kuancheng County Hospital, Kuancheng 067600, Hebei Province, China
  • Received:2015-05-05 Online:2015-05-28 Published:2015-05-28
  • Contact: Lv Yong-ming, Chief physician, Third Department of Orthopedics, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China
  • About author:Xu Fei, Master, Attending physician, Third Department of Orthopedics, Affiliated Hospital of Chengde Medical University, Chengde 067000, Hebei Province, China
  • Supported by:

    the Science and Technology Research and Development Project of Chengde City, No. 20142060

Abstract:

BACKGROUND: To reduce the amount of bleeding and the amount of hemoglobin after total knee replacement has been a key project in the clinical research in the division of bone and joint. Currently, ice therapy has been widely used in the clinic for tissue swelling and pain due to various physical and chemical factors.
OBJECTIVE: To investigate the risk factors of postoperative hemoglobin after total knee replacement and discuss the effects of ice intervention.
METHODS: 240 patients with osteoarthritis based on the random draw principles were equally divided into the treatment group and the control group. The general information, disease status, diagnosis and treatment and prognosis of the two groups were investigated. All patients were actively subjected to artificial total knee replacement. On the basis of the treatment in the control group, the treatment group received ice intervention at 2  hours after replacement for 7 consecutive days. RESULTS AND CONCLUSION: The postoperative hemoglobin decrease occurred in 34 patients, with the incidence of 14.2% among 240 patients at 7 days after replacement. Multivariate logistic regression analysis results showed that age, no ice treatment, body mass index were the main risk factors for hemoglobin decrease after total knee replacement (P < 0.05). Compared with the control group, the postoperative hemoglobin values of the treatment group were significantly higher (P < 0.05). Hemoglobin decrease values, total blood loss, blood transfusion rate, blood transfusion amount, and pain score at 3 and 7 days after replacement were significantly lower in the treatment group than in the control group (P < 0.05). The knee function excellent and good rate was 96.7% in the treatment group, and 95.8% in the control group, which showed no significant difference (P > 0.05). Results verify that clinical application of total knee replacement facilitated the knee recovery in patients with osteoarthritis, but hemoglobin decrease and bleeding existed. Active ice intervention can reduce the risk and relieve postoperative pain.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

 

Key words: Tissue Engineering, Knee Joint, Hemoglobin

CLC Number: