Effects of different graft materials and internal fixation methods on the intervertebral fusion time in atlantoaxial dislocation surgery

doi:10.3969/j.issn.2095-4344.2017.11.009

Abstract

Abstract:

BACKGROUND: Posterior screw-rod fixation is a popularized method in the treatment of atlantoaxial dislocation to eventually achieve intervertebral fusion. There are various graft materials and fixation methods that show different fusion time.

OBJECTIVE: To analyze the effect of different graft materials and internal fixation methods on the fusion time in the posterior atlantoaxial dislocation surgery.

METHODS: 286 patients with reducible atlantoaxial dislocation undergoing C_1-2posterior screw-rod fixation and obtaining successful intervertebral fusion from August 2009 to December 2015 were analyzed retrospectively. Complete pedicle screw was used for C₁ screw fixation, and pedicle or laminar screws were for C₂ screw fixation. The graft materials included autogenous or allogeneic grains of cancellous bone.

RESULTS AND CONCLUSION: The fusion time ranged from 3 to 24 months. The fusion time did not differ significantly among fixation methods (F=2.134, P=0.120). There was significant difference in the fusion time between graft materials (F=83.611, P=0.000). Besides, there was no correlation between internal fixation methods and graft materials (F=1.036, P=0.356). These results suggest that different C_1-2 posterior internal fixation methods can provide stable and reliable environment for bone fusion, and autogenous bone is more beneficial for intervertebral fusion and shortens fusion time.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

Key words: Bone Transplantation, Orthopedic implants, Atlanto-Axial Joint, Tissue Engineering

CLC Number:

R318

Zou Xiao-bao, Ma Xiang-yang, Yang Jin-cheng, Xia Hong, Wu Zeng-hui, Wang Jian-hua, Ai Fu-zhi, Zhang Kai, Yin Qing-shui. Effects of different graft materials and internal fixation methods on the intervertebral fusion time in atlantoaxial dislocation surgery[J]. Chinese Journal of Tissue Engineering Research, 2017, 21(11): 1688-1694.

Figures/Tables 3

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