Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (48): 8983-8987.doi: 10.3969/j.issn.2095-4344.2012.48.010

Previous Articles     Next Articles

Physical therapy in the fracture region with metal implants fixation

Zhang Han, Xu Yi-ming, Wan Da-qian, Bai Yue-hong   

  1. Affiliated 6th People’s Hospital of Shanghai Jiao Tong University, Shanghai 200233, China
  • Received:2012-03-12 Revised:2012-04-16 Online:2012-11-25 Published:2013-03-14
  • Contact: Bai Yue-hong, Doctor, Professor, Doctoral supervisor, Affiliated 6th People’s Hospital of Shanghai Jiao Tong University, Shanghai 200233, China aibyhw@126.com
  • About author:Zhang Han★, Studying for master’s degree, Affiliated 6th People’s Hospital of Shanghai Jiao Tong University, Shanghai 200233, China coldsusan@163.com

PDF

756

Abstract:

BACKGROUND: After fracture fixation with metal implants, is it able to take physical therapy in promoting the fracture? This exploratory experiment can be the preparation for later discussion.
OBJECTIVE: To investigate the feasibility of physical therapy after fracture fixation with metal implants and to observe the effect of physical therapy on the fracture recovery and surrounding tissues.
METHODS: Twenty-four adult white rabbits were selected and randomly divided into three groups. The models of the transaction fracture on the middle of left femur were established and fixed with plate. After fixation, the models in the control group received no treatment; the models in the intermediate-frequency group received the intermediate-frequency electro-therapy with intermediate-frequency therapeutic equioment ECM99-IIB at 4 days after fixation and lasted for 30 days; the models in the high-frequency group received the microwave therapy with microwave apparatus PM-800S at 4 days after fixation and lasted for 30 days.
RESULTS AND CONCLUSION: General observation showed that the control group had the most fibrous tissue, followed by the intermediate-frequency group, and high-frequency group had the least fibrous tissue. There was no significant difference of nerve conduction velocity among three groups (P > 0.05). Histological observation showed that there was no visible bone matrix in the control group, trabecular bone formation could be seen in the intermediate-frequency group, maturate trabecular bone could be seen in the high-frequency group. Fibrosis of muscle tissue could be seen in the control group, partly fibrosis of muscle tissue could be seen in the intermediate-frequency group and the fibrosis in the high-frequency group was not obvious. Serum biochemical indicators showed that the serum content of Ca2+ and alkaline phosphatase in the intermediate-frequency group and high-frequency group were significantly higher than those in the control group (P < 0.05). Under the experimental conditions, intermediate-frequency electro-therapy and high-frequency electro-therapy could be used after fracture fixation, and had a positive effect on the union of fracture. The effect of the high-frequency electro-therapy was better than that of the intermediate-frequency electro-therapy.

CLC Number: