Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (46): 8716-8720.doi: 10.3969/j.issn.2095-4344.2012.46.033

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Research advances in construction of tissue-engineered cartilage

Liu Shang-lun, Dong Rui, Ma Yong   

  1. Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China
  • Received:2012-02-24 Revised:2012-03-25 Online:2012-11-11 Published:2013-03-16
  • Contact: Ma Yong, Doctor, Professor, Doctoral supervisor, Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China zhongyi-my@263.n
  • About author:Liu Shang-lun★, Studying for master’s degree, Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China liushanglun1986@126.com

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Abstract:

BACKGROUND: Tissue engineering method provides a new treatment for repair of articular cartilage defects, which has broad application prospects.
OBJECTIVE: To explore the methods, researches and application prospects of the tissue-engineered cartilage construction.
METHODS: A computer-based online search of China Journal Full-text Database and Web of Science was performed for articles and reviews in Chinese and English from 1991 to 2011. The key words were “tissue engineering, cartilage defects, seed cell, scaffolds” in Chinese and English. By Screening reading titles and abstracts, relevant literatures were included. Repetitive articles with poor quality were excluded. Finally, 30 articles were included.
RESULTS AND CONCLUSION: Tissue-engineered cartilage with a variety of seed cells loaded composite scaffolds has made a great progress and shown a good role in repair of cartilage defects, but there are some specific problems to be solved in clinic.

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