Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (14): 2641-2644.doi: 10.3969/j.issn.1673-8225.2012.14.035

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Relationship between vitamin D, vitamin D receptor and hair

Zhuo Na1, Xin Yan2, Guo Guo-xiang1   

  1. 1Inner Mongolian Medical College, Hohhot  010059，Inner Mongolian Autonomous Region, China; 2Department of Dermatology, Third Affiliated Hospital (Baogang Hospital) of Inner Mongolian Medical College, Baotou  014010，Inner Mongolian Autonomous Region, China
  • Received:2012-01-09 Revised:2012-02-06 Online:2012-04-01 Published:2012-04-01
  • Contact: Xin Yan, Master, Chief physician, Department of Dermatology, Third Affiliated Hospital (Baogang Hospital) of Inner Mongolian Medical College, Baotou 014010，Inner Mongolian Autonomous Region, China xinyan69@yahoo.com.cn
  • About author:Zhuo Na★, Studying for master’s degree, Inner Mongolian Medical College, Hohhot 010059，Inner Mongolian Autonomous Region, China

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Abstract:

BACKGROUND: Increasing evidence has demonstrated that vitamin D and its receptor correlate with hair.
OBJECTIVE: To fully discuss the relationship between vitamin D, vitamin D receptor and hair follicle stem cells, hair cycle, signal transduction and alopecia.
METHODS: A computer online retrieval was performed in PubMed and CNKI database to search papers addressing the relationship between vitamin D, vitamin D receptor and hair published between November 1990 and November 2011 with the key words “ vitamin D, vitamin D receptor, hair, alopecia, gene polymorphism” in Chinese or English. Papers published recently or in the authoritative journals were selected.
RESULTS AND CONCLUSION: A total of 152 papers were initially retrieved. According to inclusion and exclusion criteria, 30 papers were selected. The current studies have shown that vitamin D and its receptor play an important role in hair and the disorder of vitamin D would lead to alopecia. Regulation of vitamin D and its receptor may be successful in preventing and treating hair disorders and is promising in future use.
 

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