Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (44): 8263-8266.doi: 10.3969/j.issn.1673-8225.2011.44.024

Previous Articles     Next Articles

Localization of GATA-4 in immune reaction product of mouse ovary

Yang Jia-zhou1, Miao Nai-zhou1, Zhao Yu-feng1, Wang Yan-mei1, Jing Cai-xia2, Ai Qing-yan1   

  1. 1Department of Human Histology and Embryology, 2Department of Parasitology, Yan’an University School of Medicine, Yan’an  716000, Shaanxi Province, China
  • Received:2011-04-16 Revised:2011-05-25 Online:2011-10-29 Published:2011-10-29
  • Contact: Ai Qing-yan, Master, Lecturer, Department of Human Histology and Embryology, Yan’an University School of Medicine, Yan’an 716000, Shaanxi Province, China aqy_2001@163.com
  • About author:Yang Jia-zhou, Associate professor, Department of Human Histology and Embryology, Yan’an University School of Medicine, Yan’an 716000, Shaanxi Province, China jiazhouy@163.com
  • Supported by:

    Special Research Program of the Education Department of Shananxi Province, No. 2010JK906*, 2010JK907*; the Natural Science Foundation of Science and Technology Department of Shaanxi Province, No. 2010JM4024*; Science Technology Research Development Plan of Yan’an City of Shaanxi Province, No. 2009KS-12*; Science Technology Research Plan Program of Yannan University, No. YD2008-04VEGF*

PDF

465

Abstract:

BACKGROUND: GATA-4 transcription factor plays a critical role in mammalian reproduction.
OBJECTIVE: To explore the characteristics and distribution of GATA-4 in immune reaction product of the ovaries of female mouse.
METHODS: Six 6-week old female mice were selected for this study. Paraffin sections of the ovaries were made and GATA-4 expression was observed by immunohistochemical ABC method and diaminobenzidine visualization.
RESULTS AND CONCLUSION: Positive expression of GATA-4 was primarily found in granulosa cells and thecal cells of the mice, with less expression in theca cells, and no expression in corepus luteum. These findings suggest that GATA-4 exists in mouse ovaries.

CLC Number: