Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (15): 2677-2680.doi: 10.3969/j.issn.1673-8225.2011.15.005

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Influence of peritendon tissues and periosteum on early healing of bone-tendon junction

Li Ai-guo, Chen Hong-hui, Jiang Bin, Dong Fei, Yang Xiao-hong, Ye Wei-xiong   

  1. Department of Orthopaedics, Guangzhou Red Cross Hospital, Guangzhou  510220, Guangdong Province, China
  • Received:2010-10-12 Revised:2010-11-29 Online:2011-04-09 Published:2013-11-06
  • About author:Li Ai-guo★, Master, Associate chief physician, Department of Orthopaedics, Guangzhou Red Cross Hospital, Guangzhou 510220, Guangdong Province, China 23494186@qq.com
  • Supported by:

    the National Natural Science Foundation of China (General Program), No.30973067*; the Medical Scientific Research Foundation of Guangdong Province, No.A2008530*

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Abstract:

BACKGROUND: Wound healing of bone-tendon junction is relatively slow due to complex structures. Repair of fibrocartilage transitional zone plays an important role in bone-tendon junction healing. 
OBJECTIVE: To explore effects of periosteum on healing of bone-tendon junction via histological methods.
METHODS: 18-weeks-old New Zealand white rabbits were randomly divided into 2 groups. The periosteum group was planted into by periosteum while the control group was only operated. Histological staining was performed at the 4, 8 and 12 weeks after operation, the absorbance value of Safranin’O positive staining was compared between two groups. 
RESULTS AND CONCLUSION: Histological examination showed the bone healing was obviously in the periosteum group at 4 and 8 weeks after operation, which characterized by trabecular bone expansion from the remaining patellar and regeneration of fibrocartilage zone at the patellar tendon-patellar healing junction. The result means that the tissue healing of the periosteum group was quicker than that of the control group. Periosteum could accelerate cellular proliferation, matrix synthesis, new bone and fibrocartilage transitional zone formation and accelerate bone-tendon junction healing. Simultaneously, histological examination can be a good judgment for detecting bone-tendon junction healing.

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