Chinese Journal of Tissue Engineering Research ›› 2020, Vol. 24 ›› Issue (29): 4673-4679.doi: 10.3969/j.issn.2095-4344.2817
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Yang Minjie1, Liu Wei2, Tu Hongfei2, Li Li2, Fei Sujuan2
Received:
2020-02-12
Revised:
2020-02-22
Accepted:
2020-03-18
Online:
2020-10-18
Published:
2020-09-14
Contact:
Fei Sujuan, Master, Chief physician, Master’s supervisor, Department of Gastroenterology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China
About author:
Yang Minjie, Master candidate, Gastroenterology Research Center, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China
Supported by:
CLC Number:
Yang Minjie, Liu Wei, Tu Hongfei, Li Li, Fei Sujuan. Protective effect of crocin in ulcerative colitis rats and its related mechanism[J]. Chinese Journal of Tissue Engineering Research, 2020, 24(29): 4673-4679.
2.2 藏红花素对溃疡性结肠炎大鼠行为学的影响 与正常组比较,模型组于饮用葡聚糖硫酸钠后3 d出现活动量减少,不喜进食,聚成一团,萎靡态,粪便有潜血,肛周黏性物增多且污浊,毛发颜色暗沉;5 d后出现肉眼血便、稀便。大鼠体质量均在第1天有所减轻,但第2天开始体质量增加,各组间无明显差异。藏红花素组及阳性对照组大鼠行为对比模型组,大鼠状态、体质量减轻及腹泻便血症程度较轻。与模型组相比,正常组结肠组织评分及疾病活动指数评分降低(P < 0.05),藏红花素各组及阳性对照组与模型组相比结肠组织评分及疾病活动指数评分降低(P < 0.05)。藏红花素高剂量组与阳性对照组比较差异无显著性意义(P > 0.05)。见表3。 "
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