Chinese Journal of Tissue Engineering Research ›› 2017, Vol. 21 ›› Issue (4): 586-590.doi: 10.3969/j.issn.2095-4344.2017.04.016

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Effect of osteoporosis on the prognosis of implant dentures

Shan Jian-liang, Zhang Qin, Hu Yang, Yao Yuan, Zhang Wei, He Hui-yu   

  1. Department of Prosthodontics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Received:2016-11-21 Online:2017-02-08 Published:2017-03-13
  • Contact: Corresponding author: He Hui-yu, M.D., Chief physician, Department of Prosthodontics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • About author:Shan Jian-liang, Studying for master’s degree, Department of Prosthodontics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Supported by:

    the Project of Urumqi Science & Technology Bureau, No. Y151310006

Abstract:

Abstract
BACKGROUND
: Due to good function and aesthetic effect, implant dentures become prevalent in osteoporotic patients with missing teeth. However, whether osteoporosis is a contraindication of dentures as well as effects of osteoporosis on the bone-implant integration have been not fully understood.
OBJECTIVE: To compare the levels of alkaline phosphatase, bone mineral density and implant stability in patients with osteoporosis and non-osteoporosis, and to explore whether the osteoporotic patients can achieve good prognosis.
METHODS: Forty patients undergoing implant dentures in the Department of Prosthodontics, the First Affiliated Hospital of Xinjiang Medical University since February 2015 were enrolled, and allotted to experimental (osteoporosis) and control (non-osteoporosis) groups (n=20 per group).
RESULTS AND CONCLUSION: The levels of salivary alkaline phosphatase, bone mineral density and initial implant stability in the experiment and control groups both were lower than those before surgery. There were significant differences in the implant stability quotient at 1 and 3 months and immediately after implantation between groups. These results indicate that osteoporotic patients undergoing implant surgery can achieve a good prognosis that is similar with non-osteoporosis ones.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Bone Density, Osteoporosis, Dentures, Tissue Engineering

CLC Number: