Chinese Journal of Tissue Engineering Research

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Non-surgical therapy for knee osteoarthritis: effectiveness evaluation using scale and biomechanical methods 

Gang Jia-hong, Mi Yi-qun, Zhang Yong-liang, Wang Hua-min   

  1. Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Online:2015-09-10 Published:2015-09-10
  • Contact: Mi Yi-qun, Master, Chief physician, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • About author:Gang Jia-hong, Studying for master’s degree, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Supported by:

    the Three-Year Action Plan Project of Shanghai Traditional Chinese Medicine supported by Shanghai Municipal Commission of Health and Family Planning and the Office of Chinese Medicine Development, No. zy3-pcpy-3-1018; Scientific Research Funds of Traditional Chinese Medicine of Shanghai Municipal Health Bureau, No. 2012J012A

Abstract:

BACKGROUND: Studies have shown that the non-surgical therapy for knee osteoarthritis is exactly effective, but there is a lack of scientific and rational evaluation system.

OBJECTIVE: To review the evaluation methods of non-surgical therapy for knee osteoarthritis in recent 5 years.

METHODS: A computer-based retrieval of PubMed, WOK, CNKI, VIP, Wanfang databases was performed to find literature related to the evaluation methods of non-surgical therapy for knee osteoarthritis. All data were primarily screened to exclude irrelevant literature. Those literatures about the evaluation methods of non-surgical therapy for knee osteoarthritis were included. Repetitive studies and untypical reports were excluded.

RESULTS AND CONCLUSION: Totally 42 articles were collected, including 28 in Chinese and 14 in English. The analysis results showed that the non-surgical treatment for knee osteoarthritis can improve knee function and the quality of life in patients, and have an exact effect and a good economic benefit. Therefore, exploring a scientific and reasonable evaluation method to guide the choice of clinical treatment for knee osteoarthritis is greatly significant, which can improve the efficacy of non-surgical therapy for knee osteoarthritis. Scale-based evaluation method is simple and practical, but the presence of a single scale has a lack of objectivity. The method of biomechanics or imaging has the advantages of objective, highly reliable, accurate, non-invasive and so on. In the future therapeutic evaluation system, the combination of subjective scale observation and objective indicators should be more recommended, and the evaluation methods of non-surgical therapy for knee osteoarthritis should be selected appropriately based on the difference of clinical therapy and effect.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Knee Joint, Osteoarthritis, Biomechanics

CLC Number: