Chinese Journal of Tissue Engineering Research ›› 2015, Vol. 19 ›› Issue (35): 5620-5624.doi: 10.3969/j.issn.2095-4344.2015.35.009

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Effects of different analgesia schemes on joint function and adverse reactions following total knee arthroplasty

Zhang Dang-sheng, Zhou Hai   

  1. Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China
  • Received:2015-07-18 Online:2015-08-27 Published:2015-08-27
  • Contact: Zhou Hai, M.D., Chief physician, Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China
  • About author:Zhang Dang-sheng, Master, Associate chief physician, Department of Anesthesiology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China

Abstract:

BACKGROUND: Severe knee pain after total knee arthroplasty is an important factor for the poor recovery of knee function after replacement. How to give a satisfactory postoperative analgesia scheme is currently a hot research.
OBJECTIVE: To explore the clinical effects of different analgesic program methods on postoperative pain and functional recovery in patients undergoing total knee arthroplasty.
METHODS: From March 2010 to February 2014, 60 patients with unilateral knee arthroplasty were randomly divided into three groups: epidural analgesia group, intravenous analgesia group, and continuous femoral nerve block analgesia group. 20 patients in each group received corresponding postoperative analgesia. Visual Analogue Scale score before replacement, 1, 6, 24, 48 and 96 hours after replacement, the recovery of range of motion at 24, 48 and 72 hours after replacement, KSS score of the knee and adverse reactions after replacement were recorded and compared in each group. 
RESULTS AND CONCLUSION: Compared with the preoperative data, Visual Analogue Scale score was reduced in continuous femoral nerve block analgesia group at 1, 24, 48 and 96 hours after replacement (P < 0.05). The recovery of range of motion was best in the continuous femoral nerve block analgesia group, followed by epidural analgesia group, and it was poorest in the intravenous analgesia group (P < 0.05). Compared with the preoperative data, postoperative KSS scores increased at 1 and 3 months after replacement in the three groups (P < 0.05). Compared with the continuous femoral nerve block analgesia group, knee joint function score was 
decreased in the intravenous analgesia group (P < 0.05). Results verified that continuous femoral nerve block analgesia had good overall effects, helped the recovery of postoperative joint function, and was safe and reliable.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Tissue Engineering, Knee Joint, Femoral Nerve

CLC Number: