Microfracture and osteochondral transplantation in the treatment of articular cartilage defects

doi:10.3969/j.issn.2095-4344.2015.15.004

Abstract

Abstract:

BACKGROUND: Both microfracture and osteochondral transplantation are effective tools in the clinical treatment of articular cartilage defects.
OBJECTIVE: To observe the implementation results of microfracture and osteochondral transplantation in the treatment of articular cartilage defects.
METHODS: The clinical data of 50 cases (50 knees) of articular cartilage defects were retrospectively analyzed. There were two groups according to surgical repair methods: autogenous osteochondral transplantation+ microfracture in observation group (n=25), and microfracture in control group (n=25). Patients in the two groups were followed up for over 24 hours to compare the Hospital for Special Surgery scores, clinical efficacy, adverse effects and complications.
RESULTS AND CONCLUSION: The number of patients whose Hospital for Special Surgery score was > 85 points and 60 to 85 points in the observation group was significantly larger than that in the control group (P < 0.05), and the total treatment effective rate of patients in the observation group was significantly higher than that of the control group (92% vs. 60%, P < 0.05). No complications occurred in both two groups. These findings indicate that osteochondral transplantation has better implementation results in the treatment of articular cartilage defects than microfracture.

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

全文链接：

Key words: Fractures, Bone, Cartilage, Bone Transplantation

CLC Number:

R318

Yang Jian, Pang Xian-lun, He Jiang-meng . Microfracture and osteochondral transplantation in the treatment of articular cartilage defects[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(15): 2315-2319.

Figures/Tables 2

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