Antibacterial activities of modified dentin adhesive agent against Streptococcus mutans

doi:10.3969/j.issn.2095-4344.2013.21.015

Abstract

Abstract:

BACKGROUND: During the treatment of dental caries with bonding repair technique, residual bacteria following the preparation of cavities can survive a long time between the tooth structure and dental prosthesis, which can cause secondary caries or chronic inflammation of the pulp.
OBJECTIVE: To evaluate the antibacterial effects of resin-based adhesive modified with the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide against Streptococcus mutans.
METHODS: Experimental antibacterial adhesive specimens (GLUMA Comfort Bond) covered with different concentrations of antibacterial monomers (0 as negative control, 1%, 2%, 3%, 4% 12-methacryloyloxydodecylpyridinium bromide) were prepared, and their antibacterial effects were investigated by the measurement of bacteria liquid absorbance, pH value which contained experimental antibacterial adhesive specimens after 18-hour culture. Clearfil Protect Bond was used as positive control.
RESULTS AND CONCLUSION: There was statistical difference in antibacterial effects between the negative control and positive control. The experimental adhesive specimens incorporated with 1% and 2% monomers showed antibacterial activities against Streptococcus mutans similar as the negative control (P > 0.05). There was no statistical difference in antibacterial effects between the positive control and experimental adhesive specimens incorporated with 3% and 4% monomers (P > 0.05). These findings indicate that experimental adhesive specimens containing 3% and 4% 12-methacryloyloxydodecylpyridinium bromide monomers showed better antibacterial activities.

Key words: biomaterials, tissue-engineered oral materials, antibacterial activity, 12-methacryloyloxydodecylpyridinium bromide, composite resin, Streptococcus mutans, monomer, adhesive, provincial grants-supported paper

CLC Number:

R318

Liu Mei-tian, Nie Hong-bing, Zhang Jin-ting, Zhou Hai-jing. Antibacterial activities of modified dentin adhesive agent against Streptococcus mutans[J]. Chinese Journal of Tissue Engineering Research, doi: 10.3969/j.issn.2095-4344.2013.21.015.

Figures/Tables 2

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