Comparison of bone mineral density levels in women of different ages during middle and late pregnancies

doi:10.3969/j.issn.2095-4344.1902

Abstract

Abstract:

BACKGROUND: With the increasing awareness of eugenics and the opening up of the National Policy of Second Child, people pay more and more attention to health care during pregnancy, especially nutrition intake and bone health status during pregnancy.
OBJECTIVE: To provide scientific and rational nutrition guidance for maternal health care and prevent bone mineral density from decreasing during pregnancy by comparing and analyzing the changes of bone mineral density in women of different ages and gestational periods.
METHODS: Totally 531 pregnant women admitted to the hospital from June 2017 to April 2018 were selected. All participants were native residents of Guangxi Zhuang Autonomous Region, volunteered to the trial, and signed the informed consents. They were signed by pregnancy week and age. The bone mineral density of radius of pregnant women in each group was measured by ultrasound. Correlation analysis of age, pregnancy week and bone mineral density was conducted.
RESULTS AND CONCLUSION: (1) There was no significant difference in the bone mineral density decrease between middle and late pregnant women (P > 0.05). (2) The speed of sound and T values of pregnant women of different ages had significant difference, and increased with age (P < 0.05). (3) The speed of sound and T values in the second trimester increased with age, and there was a significant difference (P < 0.05). There was no significant difference in the bone mineral density between the different age groups in the third trimester (P > 0.05). (4) These results indicate that bone mineral density changes should be regularly detected in the middle and late pregnancies, and the calcium deficiency and bone condition of pregnant women should be known in time. Nutritional intervention should be carried out in the early stage to ensure maternal bone health and normal fetal development.

Key words: pregnant women, age, bone mineral density, radius, ultrasound, middle pregnancy, late pregnancy

CLC Number:

Huang Liqian, Kong Cunqing, Shu Wenbo, Zhou He, Lai Qiurong, Chen Run, Tang Cheng, Yang Yazhu, . Comparison of bone mineral density levels in women of different ages during middle and late pregnancies[J]. Chinese Journal of Tissue Engineering Research, 2019, 23(35): 5582-5586.

Figures/Tables 4

References

[1]Yun KY, Han SE, Kim SC, et al. Pregnancy-related osteoporosis and spinal fractures. Obstet Gynecol Sci. 2017;60(1):133-137.

[2]Kovacs CS. Bone development and mineral homeostasis in the fetus and neonate: roles of the calciotropic and phosphotropic hormones. Phys Rev. 2014;94(4):1143-1218.

[3]Kovacs CS. Calcium, phosphorus and bone metabolism in the fetus and newborn. Early Human Dev. 2015;91(11):623-628.

[4]Miyatake N, Muta H, Murota C, et al. Bone status assessment in Japanese subjects using speed of sound along the tibia. Chi Med J. 2002;115(2):254.

[5]Karlsson MK, Ahlborg HG, Karlsson C. Maternity and bone mineral density. Acta Orthopaedica.2005;76(1):2-13.

[6]杨晓红,熊琼英,左惠萍,等.妊娠期糖尿病患者骨密度检测及影响因素分析[J].中国骨质疏松杂志,2015,21(6):708-711.

[7]谢乐瑜,宋兵文,邓如芝,等.产后妇女骨密度影响因素分析[J].实用预防医学,2011,18(7):1300-1301.

[8]赵银花,刘春源,温勇,等.妊娠期妇女超声跟骨骨密度测定的临床观察[J]. 婚育与健康·实用诊疗,2014,22(7):45-46.

[9]张欣.妊娠期骨密度检测对孕期饮食指导的意义[J].基层医学论坛,2013,17(18):2433-2434.

[10]李晋娥,司丽芬,王海生.妊娠期妇女不同孕期骨量监测结果分析[J].中国实用医刊,2014,41(22):66-67.

[11]郑彦,杨洋.妊娠期妇女骨密度状况监测分析[J].护理研究,2013, 27(17):1745-1746.

[12]Della Martina M, Biasioli A, Vascotto L, et al. Bone ultrasonometry measurements during pregnancy. Arch Gynecol Obstet. 2010;281(3):401-407.

[13]Moller UK, Viqstreym S, Mosekilde L, et al. Changes in bone mineral density and body composition during pregnancy and postpartum. A controlled cohort study. Osteoporos Int. 2012; 23(4):1213-1223.

[14]胡丽萍.妊娠期骨密度检测对孕期的指导作用[J].中国卫生标准管理,2016,7(2):168-169.

[15]杨凤英,海向军.妊娠期妇女骨密度的研究进展[J].中国骨质疏松杂志,2014,20(7):854-857.

[16]武亮,祁桠楠,李丽,等.296例妊娠妇女超声骨密度检测分析[J]. 医学信息,2016,29(6):300-301.

[17]江滢. 3320例孕妇骨密度测定结果分析[J].中国妇幼保健,2012, 27(28):4377-4378.

[18]王士艳,蒋洁,蒋霞. 1056例产妇骨密度检测结果分析[J].实用临床医药杂志,2017,21(21):228-229.

[19]徐艳红.不同年龄段孕产妇的骨密度表现比较[J].河北医药,2016, 38(1):108-109.

[20]王凯.骨密度检测联合早期干预对孕妇钙丢失的影响[J].医疗装备, 2015,29(15):181-182.

[21]凌静,戴新民,叶细锋,等. 19708例健康体检人员跟骨定量超声检测骨密度结果分析[J].中华保健医学杂志,2011,13(2):149-150.

[22]张红,王芳芳,白云,等.不同年龄孕期女性骨密度的比较分析[J]. 中国药物与临床,2014,14(1):16-18.

[23]李俊.武昌区孕妇骨密度及影响因素分析[J].医学信息,2013，26(22):80-80.

[24]吴秀菊,林文雅,黎亮儿.不同孕期孕妇骨密度干预结果与对比分析[J].现代诊断与治疗,2015,26(5):1147-1148.

[25]谢晓敏,梁慧芬.不同孕期超声桡骨远端外侧骨密度调查研究[J]. 临床和实验医学杂志,2015,14(10):809-811.

[26]龚华虹,刘海静,蒋维,等.孕期钙营养指导及运动干预对孕妇骨密度的影响[J].中国妇幼保健,2013,28(11):1734-1735.

[27]邓红.广州市30-49岁女教师骨质与营养状况的相关性分析[J].中国组织工程研究,2018,22(4):499-504.

[28]Kyoko Y, Junko I. The effects of dietary calcium and protein intake on changes in bone mineral density during early and late stages of pregnancy. Nihon Koshu Eisei Zasshi. 2010; 57(10):871-880.

[29]Kovacs CS. Calcium and bone metabolism disorders during pregnancy and lactation. Endocrinol Metab Clin North Am. 2011;40(4):795-826.