Chinese Journal of Tissue Engineering Research ›› 2018, Vol. 22 ›› Issue (24): 3930-3936.doi: 10.3969/j.issn.2095-4344.0234

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Clinical effect of reconstruction of single-bundle versus double-bundle posterior cruciate ligament under arthroscopy: a Meta-analysis

Gao Peng1, Gao Bin2, Gu Pei-lun1, Li Yue-jun1, Yang Peng-fei1, Qin Qi1, Wang Wei-shan1, Dong Jin-bo1   

  1. 1Orthopedic Center, the First Affiliated Hospital of the Medical College, Shihezi University, Shihezi 832000, Xinjiang Uygur Autonomous Region, China; 2Korla Reserve Artillery Regiment, Korla 841000, Xinjiang Uygur Autonomous Region, China
  • Received:2017-12-23
  • Contact: Dong Jin-bo, Chief physician, Master’s supervisor, Orthopedic Center, the First Affiliated Hospital of the Medical College, Shihezi University, Shihezi 832000, Xinjiang Uygur Autonomous Region, China
  • About author:Gao Peng, Master candidate, Orthopedic Center, the First Affiliated Hospital of the Medical College, Shihezi University, Shihezi 832000, Xinjiang Uygur Autonomous Region, China

Abstract:

BACKGROUND: Arthroscopic surgery is often used for posterior cruciate ligament injury, but the specific reconstruction method is still controversial. The clinical efficacy of single-bundle and double-bundle
reconstruction still remains unclear.
OBJECTIVE: To evaluate the clinical efficacy of arthroscopic single-bundle versus double-bundle posterior cruciate ligament reconstruction. 
METHODS: PubMed, Embase, the Cochrane library, CNKI, and WanFang databases were retrieved for the articles addressing the curative effect of arthroscopic single-bundle versus double-bundle posterior cruciate ligament reconstruction. Based on the inclusion and exclusion criteria, the literature screen and quality assessment were conducted by two researchers, and a Meta-analysis was performed on Revman5.3 software.
RESULTS AND CONCLUSION: A total of 11 eligible articles were included, including 5 randomized controlled trials and 6 non-randomized controlled trials, involving 529 cases of posterior cruciate ligament injury. Meta-analysis results showed that the postoperative International Knee Documentation Committee scores in the double-bundle reconstruction group were superior to those in the single-bundle reconstruction group (RR=0.88, 95%CI (0.79, 0.98), P=0.02]. The postoperative Lysholm score (MD=-0.68, 95%CI (-1.59, 0.24), P=0.15) and Tegner scores (MD=-0.16, 95%CI (-0.37, 0.04), P=0.12) showed no significant difference between two groups. The knee flexion 90° to the evaluation of the stability in double-bundle reconstruction group was superior to that in the single-bundle reconstruction group (MD=1.07, 95%CI (0.28, 1.87), P=0.008). In summary, both reconstructions are effective, only in the knee stability and International Knee Documentation Committee scores,  double-bundle posterior cruciate ligament reconstruction is superior to single-bundle posterior cruciate ligament reconstruction. However, because of the quality and size of the literature included, more high quality randomized controlled trials need to be collected for in-depth investigation.

中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松组织工程

Key words: Posterior Cruciate Ligament, Arthroscopy, Meta-Analysis, Tissue Engineering

CLC Number: