Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (25): 4686-4691.doi: 10.3969/j.issn.1673-8225.2012.25.026

Previous Articles     Next Articles

Surface modification and biocompatibility of medical nickel-titanium shape memory alloys

Du Jian1, Ding Yuan-fa2, Su Xiang-dong2, He Li2, Hao Wei-chang3, Wang Tian-min3   

  1. 1School of Materials and Construction Engineering, Guizhou Normal University, Guiyang 550001, Guizhou Province, China;
    2Guizhou Academy of Sciences, Guiyang 550001, Guizhou Province, China;
    3School of Physics and Nuclear Energy Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China
  • Received:2011-11-02 Revised:2011-11-21 Online:2012-06-17 Published:2013-11-04
  • Contact: 苏向东，博士，硕士生导师，研究员，贵州科学院，贵州省贵阳市 550001 suxingdong01@sina.com
  • About author:Du Jian★, Master, Lecturer, School of Materials and Construction Engineering, Guizhou Normal University, Guiyang 550001, Guizhou Province, China 573275875@qq.com

PDF

1292

Abstract:

BACKGROUND: Near-equiatomic nickel-titanium shape memory alloy can be used as a type of ideal biological implant material based on its deformation rate of 8%, million times in the number of cycles, excellent corrosion resistance and low elastic modulus, low magnetism, and radiopacity.
OBJECTIVE: To discuss the surface modification and biocompatibility of the medical near-equiatomic nickel-titanium shape memory alloy.
METHODS: A computer-based online search was performed in PubMed database and Wanfang database for literatures from January 1990 to December 2008 related to surface chemical treatment and chemical modification of medical nickel-titanium shape memory alloy and dissolvability of nickel after implantation of the alloy into biological tissues.
RESULTS AND CONCLUSION: Near-equiatomic nickel-titanium shape memory alloy has high nickel content. However, there has been controversy about the safety after long term implantation of the alloy in vivo. Alloy surface modification is an effective way to improve the biocompatibility of implants. The release of Ni ion can be decreased by surface modification of nickel-titanium shape memory alloy, and many related research works have been done by domestic and overseas scholars. However, studies about the metabolic process of Ni ion in vivo after implantation of nickel-titanium alloy are not comprehensive and systematic.

CLC Number: