Abstract:

BACKGROUND: Tissue engineering construction technology provides a new approach for esophageal defect repair.
OBJECTIVE: According to the literature retrieval results, to multivariately analyze the literatures on tissue-engineered esophagus through China National Knowledge Infrastructure (CNKI) database and Science Citation Index (SCI) database and to explore the future development tendency of tissue-engineered esophagus.
METHODS: A retrieval was performed for the literature of tissue-engineered esophagus, using the key words of “esophagus, tissue engineering, esophageal epithelial cells, scaffold construction” between January 2002 and December 2011 in CNKI database and SCI database. The retrieval results were analyzed, and the trends were described in words and graphics.
RESULTS AND CONCLUSION: (1)The literature of tissue-engineered esophagus between January 2002 and December 2011 was not too much. The overall number of literature had an upward trend from 2002 to 2011. (2)Journal of Clinical Rehabilitative Tissue Engineering Research published most papers in this field. There were 10 fund projects on the tissue-engineered esophagus. United States published more literature than other countries, which play an important role in the field of the tissue-engineered esophagus. Many of literatures were published from Medical University of Graz, Nanyang Technological University, and University of Washington. (3)This paper provides a valuable reference for researchers to understand the overview and present situation of this field.