Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (6): 1133-1136.doi: 10.3969/j.issn.1673-8225.2012.06.040

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Function of fetal microchimerism during disease and tissue repair in parous women★

Zhang Guo-hui1, Ji Hong-yu2   

  1. 1Department of Forensic Medicine, Hebei North University, Zhangjiakou  075000, Hebei Province, China; 2Department of Gynecology and Obstetrics, the First Affiliated Hospital of Hebei North University, Zhangjiakou  075000, Hebei Province, China
  • Received:2011-06-28 Revised:2011-09-26 Online:2012-02-05 Published:2012-02-05
  • About author:Zhang Guo-hui★, Master, Professor, Department of Forensic Medicine, Hebei North University, Zhangjiakou 075000, Hebei Province, China yxyzgh@yahoo.com.cn

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Abstract:

BACKGROUND: Fetal microchimerism is a kind of stem cells which comes from fetus in pluripara. The research on fetal microchimerism is a hotspot because it may affect the health condition of pluripara.
OBJECTIVE: To introduce the methods of how to detect fetal microchimerism, and the function of fetal microchimerism during disease and tissue repair of the mother.
METHODS: “Fetal microchimerism” was used as a key word, and papers published before 2011-05-20 were retrieved in PubMed. Repetitive papers were eliminated.
RESULTS AND CONCLUSION: Totally 655 papers were retrieved, and finally 26 were reviewed. There are several methods used for fetal microchimerism detecting, and fetal microchimerism may pay an important role in the pathomechanism of pluripara autoimmune diseases, cancer and tissue repair.

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