Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (4): 748-751.doi: 10.3969/j.issn.1673-8225.2012.04.041

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Bone marrow transplantation and core decompression for treatment of early necrosis of the femoral head: A non-randomized controlled study  

Qin Xue-liu, Xin Xiao-dong, Wang Da-wei, Chen Yue-ping, Lin Zong-han, Han Jie, Qin Jie   

  1. Department of Orthopaedics, Affiliated Ruikang Hospital of GuangXi Traditional Chinese Medical University, Nanning  530011, Guangxi Zhuang Autonomous Region, China
  • Received:2011-06-14 Revised:2011-08-26 Online:2012-01-22 Published:2014-04-04
  • Contact: 辛晓东，硕士，广西中医学院附属瑞康医院骨科，广西壮族自治区南宁市 530011 xinxin0403@hotmail.com
  • About author:Qin Xue-liu, Chief physician, Department of Orthopaedics, Affiliated Ruikang Hospital of GuangXi Traditional Chinese Medical University, Nanning 530011, Guangxi Zhuang Autonomous Region, China qinxueliu2008@163.com
  • Supported by:

    Program Subject of Health Department of Guangxi Zhuang Autonomous Region, No. Z2007134*

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Abstract:

BACKGROUND: Bone marrow transplantation for the treatment of femoral head necrosis becomes a hot research topic in recent years, while the role of core decompression in the treatment is in dispute. The combined therapeutic effect of core decompression and bone marrow transplantation in treatment of femoral head necrosis is unclear.
OBJECTIVE: To explore the combined therapeutic effect of core decompression and bone marrow transplantation in treatment of early necrosis of the femoral head.
METHODS: Patients with early non-traumatic necrotic femoral head were included. Twenty of them with 25 hips treated by core decompression and concentrated bone marrow transplantation were taken as treatment group. Twenty patients with 23 hips in the control group underwent simple core decompression.
RESULTS AND CONCLUSION: Following 6-36 months follow-up, the total efficiency rate of the treatment group was 84% and that was 65% in the control group according to the hip function criteria of Japanese Orthopaedic Association and the Radiology Stage System of bone necrosis of Pennsylvania State University. Core decompression combined with bone marrow transplantation have better curative effects in treatment of early femoral head necrosis based on their small damage and good curative effects, however, their long-term effect is still unclear.

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