Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (4): 638-641.doi: 10.3969/j.issn.1673-8225.2012.04.016

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Preliminary clinical results of artificial disc replacement for degenerative disc disease in 16 cases

Wu Liang1, Sun Xiao-liang1, Zhang Lei1, Wu Guo-feng1, Zhou Jian1, Yve Cartonne2○, Pascal Moussellard2○   

  1. 1Department of Orthopedics, the First People’s Hospital of Changzhou, Soochow University, Changzhou  213003, Jiangsu Province, China; 2Pitie-Salpetriere Hospital, the 6th University of Paris, France
  • Received:2011-07-25 Revised:2011-11-12 Online:2012-01-22 Published:2014-04-04
  • About author:Wu Liang☆, Doctor, Associate chief physician, Master’s supervisor, Department of Orthopedics, the First People’s Hospital of Changzhou, Soochow University, Changzhou 213003, Jiangsu Province, China drwuliang@tom.com
  • Supported by:

    the Special Foundation for Young Scientists of Changzhou Municipal Health Bureau, No. QN200805*

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Abstract:

BACKGROUND: Simple discectomy and spinal fusion surgery were the classical methods for the degenerative disc disease. Comparing to them, artificial disc replacement (ADR) showed more theoretical superiority.
OBJECTIVE: To present the preliminary clinical results of ADR for the treatment of degenerative disc disease.
METHODS: From May 2007 to October 2010, ADR were preformed on 16 cases for the treatment of degenerative disc disease. 9 males and 7 females with average age of 40.5 years underwent ADR.
RESULTS AND CONCLUSION: The follow-up time averaged 21.5 months (6-36 months). Postoperative visual analogue scale, Oswestry Disability Index and intervertebral height were significantly improved as compared with those in preoperation (P < 0.01). The postoperative range of motion (ROM) of the involved lumbar segment was effectively kept. The ROM before and after operation showed no significant difference (P > 0.05). ADR can acquire satisfactory preliminary clinical results for the treatment of degenerative disc disease. However, further research is needed to study its long-term impact.

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