Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (44): 8337-8340.doi: 10.3969/j.issn.1673-8225.2011.44.042

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Clinical analysis of Rh (D) incompatibility in a liver transplantation patient

Shang Li-ming, Peng Min-hao, Qin Xiao, Guo Ya, Xiao Kai-yin, Peng Tao   

  1. Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning   530021, Guangxi Zhuang Autonomous Region, China
  • Received:2011-06-26 Revised:2011-07-16 Online:2011-10-29 Published:2011-10-29
  • Contact: Peng Tao, Doctor, Professor, Doctoral supervisor, Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China pengtaocn@hotmail.com
  • About author:Shang Li-ming★, Master, Attending physician, Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China sxyqslm@163.com
  • Supported by:

    Scientific Research Foundation Key Program of Guangxi Medical Care and Health, No.Zhong201018*

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Abstract:

BACKGROUND: Blood type incompatibility organ transplantation can result in severe rejection, graft versus host disease and hemolytic reaction.
OBJECTIVE: To retrospectively analyze the liver transplantation method of RH(D)-negative patients with liver cancer using the RH (D)-positive donor and to investigate the feasibility of the method of transplantation based on related literatures.
METHODS: One donor liver with Rh (D)-positive was transplanted to a patient of liver cancer with Rh (D)-negative. Then the donor liver with Rh (D)-positive was well lavaged, bleeding in operation should be minimized, and products of blood with Rh (D)-positive was infused. Follow-up and effects were observed.
RESULTS AND CONCLUSION: One donor liver with Rh (D)-positive was successfully transplanted to a patient of liver cancer with Rh (D)-negative. The operation was smoothly performed. There were no acute and chronic rejection and blood transfusion-related complications after operation. The patient has survived for 1 year with normal liver function. These finding suggest that because there are no acute and chronic rejection and blood transfusion-related complications happened, so a donor liver with Rh (D)-positive can be transplanted into a patient with liver cancer with Rh (D)-negative blood after full irrigation and good clinical results have been acquired.

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