Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (44): 8189-8192.doi: 10.3969/j.issn.1673-8225.2011.44.006

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Extro-pulmonary bacterial infection after liver transplantation: An analysis of 52 cases from one institute during 9-year follow-up period

Song Ji yong1, Du Guo-sheng1, Zhu Zhi-dong1, Zheng De-hua1, Shi Bing-yi2   

  1. 1Second Department of Hepatobiliary Surgery, 2Organ Transplantation Center, the 309 Hospital of PLA，Beijing  100091, China
  • Received:2011-04-12 Revised:2011-07-07 Online:2011-10-29 Published:2011-10-29
  • Contact: Shi Bing-yi, Master, Doctoral supervisor, Chief physician, Organ Transplantation Center, the 309 Hospital of PLA，Beijing 100091, China shibingyi@medmail. com.cn
  • About author:Song Ji-yong★, Master, Attending physician, Second Department of Hepatobiliary Surgery, the 309 Hospital of PLA，Beijing 100091, China sjy0723@sina.com

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Abstract:

BACKGROUND: Bacterial infection after liver transplantation is one of the frequent complications. Although extro-pulmonary infection seldom threatens the lives of patients, extro-pulmonary infection after liver transplantation is significantly higher than that after other obdominal operations. Extro-pulmonary infection after liver transplantation aggravates patients’ suffering and prolongs the hospitalization period, so it remains an intractable clinical problem.
OBJECTIVE: To explore the risk factors of extro-pulmonary bacterial infection after liver transplantation and summarize the prevention and treatment programs for these patients.
METHODS: 52 extro-pulmonary bacterial infection patients who underwent liver transplantation were retrospectively analyzed. The risk factors, disease characteristics, common pathogenic bacterias and treatment prescription were summarized.
RESULTS AND CONCLUSION: Postoperative extro-pulmonary bacterial infection was diagnosed in 52 of 356 patients who underwent liver transplantation. There were 36 patients with infection of incisional wound, 13 patients with infection of abdominal cavity, 6 patients with infection of biliary tract in this group. Three patients were found with infection at two positions. Pathogenic bacterias were dectected in these patients. 32 patients suffered from single bacterial infection and five patients had combined bacterial infection. No patients died because of postoperative extro-pulmonary bacterial infection. The pathogenic bacterias included pseudomonas aeruginosa, escherichia coli, staphylococcus aureus, enterococcus faecalis, and enterococcus faecium. The possible risk factors included over 10 000 mL bleeding, biliary complication, retransplantation, fulminating hepatic failure and severe ascites receptors. These findings show that postoperative extro-pulmonary bacterial infection is one of common complications after liver transplantation. Timely detection, reasonable prevention and treatment can relieve patients’ pain and shorten hospitalization time period.

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