Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (37): 6913-6916.doi: 10.3969/j.issn.1673-8225.2010.37.017

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Hematopoietic function of model rats under intermittent hypoxic training and exercise

Ru Tie-lin1, Hao Xuan-ming2   

  1. 1 Department of Physical Education, Xi’an University of Science and Technology, Xi’an 710054, Shaanxi Province, China; 2 College of Sports Science, South China Normal University, Guangzhou   510631, Guangdong Province, China
  • Online:2010-09-10 Published:2010-09-10
  • About author:Ru Tie-lin★, Master, Lecturer, Department of Physical Education, Xi’an University of Science and Technology, Xi’an 710054, Shaanxi Province, China rtl_7608@yeah.net

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Abstract:

BACKGROUND: Previous studies have demonstrated that hypoxic training can promote aerobic capacity by improving hematological indexes, but the effects of different intermittent hypoxic training models on hematological indexes are rarely reported.
OBJECTIVE: To investigate the effect of intermittent hypoxic training on hematopoietic function in rats.
METHODS: A total of 96 SD rats were randomly divided into 4 groups: intermittent hypoxic training group, swimming group, intermittent hypoxic training + swimming group, and control group. Intermittent hypoxic training group and swimming group underwent intermittent hypoxic training and swimming training respectively; intermittent hypoxic training and swimming training were carried out simultaneously in intermittent hypoxic training +swimming group; control group underwent freely moving and feeding. All groups underwent formal training for 4 weeks. Twenty-four hours after 1-, 2-, 3-, 4- week formal training, blood sample from tail vein was collected to detect hemoglobin, red blood corpuscle, and hematocrit levels.
RESULTS AND CONCLUSION: After 4-week training, three types of intervention models have different effects on routine blood indexes; however, hemoglobin, red blood corpuscle, and hematocrit levels changed most significantly in intermittent hypoxic training + swimming group. It is indicated that intermittent hypoxic training and exercise are superior to intermittent hypoxic training or exercise training in case of improving hematopoietic function of rats.

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