Chinese Journal of Tissue Engineering Research ›› 2024, Vol. 28 ›› Issue (26): 4101-4105.doi: 10.12307/2024.438
Zhang Shudong1, Huang Yilin1, Yao Qi2
Received:
2023-07-12
Accepted:
2023-08-09
Online:
2024-09-18
Published:
2023-09-28
Contact:
Yao Qi, MD, Chief physician, Master’s supervisor, Department of Joint, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China
About author:
Zhang Shudong, Master, physician, Second Department of Orthopedics, The First Affiliated Hospital of Henan University, Kaifeng 475000, Henan Province, China
Supported by:
CLC Number:
Zhang Shudong, Huang Yilin, Yao Qi. Punicalagin treats postmenopausal osteoporosis by promoting osteogenesis[J]. Chinese Journal of Tissue Engineering Research, 2024, 28(26): 4101-4105.
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2.3 安石榴苷对绝经后骨质疏松症大鼠的治疗作用 由图3A可知,卵巢切除组骨小梁较假手术组稀疏,结构紊乱,治疗组骨小梁数量有所增加,但仍较假手术组少。由图3B可知,卵巢切除组骨密度较假手术组显著降低,差异有显著性意义(P < 0.05),治疗组骨密度升高,与卵巢切除组存在显著差异(P < 0.05),但仍低于假手术组。卵巢切除组的骨体积分数、骨小梁厚度、骨小梁数目均较假手术组降低,差异有显著性意义(P < 0.05),治疗组骨体积分数、骨小梁厚度、骨小梁数目均有改善,与卵巢切除组存在显著差异(P < 0.05),但仍低于假手术组。由图3C可知,卵巢切除组血清P1NP水平较假手术组显著降低,差异有显著性意义(P < 0.05);与卵巢切除组比较,治疗组P1NP水平升高,差异有显著性意义(P < 0.05),但仍低于假手术组。"
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