Design
Comparative observation.
Time and setting
The study was completed in the Department of Orthopedics, Affiliated Hospital of Xiangnan University from January 2000 to January 2012.
Subjects
Totally 176 patients with osteoporotic hip fracture included 63 males and 113 females, with a mean age of (76.7±6.3) years (range from 65 to 95 years). Eighty-four cases suffered from interchanteric fracture, including 27 males and 57 females, with a mean age of (77.7±9.1) years (range from 66 to 95 years). All fractures in the cases of interchanteric fracture were divided according to Evans-Jensen classification standard, Ⅰ type in 11 cases, Ⅱ type in 25 cases, Ⅲ type in 38 cases, Ⅳ type in 10 cases. Seven cases were treated by conservative methods, 34 cases by dynamic hip screw, 18 cases by cannulated pull screw, seven cases by anatomical plate, 12 cases by artificial bipolar femoral head replacement and six cases by total hip replacement. Ninety-two cases suffered from femoral neck fracture, including 36 males and 56 females, with a mean age of (74.6±8.2) years (range from 65 to 92 years). All fractures in these 92 cases of femoral head fracture were divided according to Garden classification standard, Ⅰ type in 10 cases, Ⅱ type in 23 cases, Ⅲ type in 31 cases, and Ⅳ type in
28 cases. Forty cases were treated by artificial bipolar femoral head replacement, 37 cases by total hip replacement, and 15 cases by cannulated pull screw.
Inclusion criteria[1-2]: (1) Patients all aged ≥65 years old; (2) bone marrow density value was less than or equal to 2.5 standard deviation of normal young values; (3) patients were hospitalized for hip fractures; (4) informed consent was obtained from patients who were approved by the hospital ethic committee.
Methods
Preoperative preparation
Related examinations were done for a comprehensive assessment of the patient’s body. Concomitant diseases were treated first, as well as infections. Fasting blood glucose was less than 8.0 mmol/L in diabetics, and patients with thrombocytopenia were given platelet drugs and transfusion of fresh platelets, and finally the number of platelets accounted for over 8.0×1010/L. Anemia patients were given drug therapy or transfusion of red blood cells to increase the hemoglobin level up to 100 g/L or more. Three days before operation, antibiotics were used. Under strict aseptic conditions, preoperative catheterization was performed.
Treatments
Of the 84 patients with interchanteric fracture, seven cases were treated by conservative methods, 34 cases by DHS, 18 cases by cannulated pull screw, seven cases by anatomical plate, 12 cases by artificial bipolar femoral head replacement and six cases by total hip replacement. Of the 92 patients with femoral neck fracture, 40 cases were treated by artificial bipolar femoral head replacement, 37 cases by total hip replacement, and 15 cases by cannulated pull screw.
Dynamic hip screw intervention
An incision was given from greater trochanter apex to the distal on lateral femur. Under the perspective of C-arm X-ray machine, the compression screw probe was inserted into the femoral neck, then the length was measured and the screw was implanted, and lateral plate was also implanted, the cortical screw was used to fix plate and femoral shaft. To prevent rotation deformity of femoral head, an anti-rotation screw was inserted into the top of the compression screw.
Cannulated screw and anatomical plate interventions
An incision was given from greater trochanter apex to the distal on lateral femoral proximal, followed by traction reduction. Under the perspective of C-arm X-ray machine, the collodiaphyseal angle was ensured as 130° and anteversion angle as 10°-15°: (1) Cannulated screw group, a parallel or“品”shaped probe was inserted at 2.0-3.0 cm below the greater trochanter apex, through the femoral neck, then a satisfactory position was achieved by C-arm X-ray and the length of screw was measured, 2-3 hollow screws were used for fixation. (2) Anatomical plate group, anatomical plate was inserted with the plate top screwed three cancellous bone screws and the plate bottom fixed by cortical screws and femoral shaft. Tensile screw was used to fix greater and lesser trochanter, as well as bone mass.
Bipolar femoral head replacement and total hip replacement interventions
An incision, 6-10 cm long, was performed at lateral hip, keeping gluteus medius muscle in the femoral trochanter top, removing femoral head and bone fragments at 1.0-1.5 cm of joint capsule away from lesser trochanter, protecting the bone fracture mass of the greater and lesser trochanter, temporary fixation with Kirschner wire was given for fracture reduction to achieve anatomic reduction: (1) Bipolar femoral head replacement: osteoporosis patients did not need forced reaming to prevent intraoperative femoral fractures, femoral pedicle with appropriate length was suggested, pedicle was 2-3 cm longer than distal fracture line, then fixed with bone cement in marrow cavity, the severely crushing bone mass of greater trochanter was tied using wire. (2) Total hip replacement group, acetabular bone sclerosis was wore off using burr and the surrounding inflammatory granulation tissues were cleared until the bone surface was fresh, other steps were same with bipolar femoral head replacement.
Postoperative management
Postoperative antibiotics were used to prevent infection and the drainage tube was removed within postoperative 24 hours to reduce retrograde infection. Prevention of deep vein thrombosis: the prevention of deep vein thrombosis twice per day was given using manual or cycle therapeutic apparatus, low molecular heparin anticoagulation to prevent thrombus. From postoperative 1 day, the patients were guided to do activities in bed, also informed of the limits of motion range. Hip joint activities were not allowed in patients undergoing hip fracture fixation; hip flexion should restrict to 90° within 6 weeks for patients with prosthetic replacement. The posterior prosthesis replacement patients were also required to forbid hip joint adduction and rotation within 6 weeks. A pillow under legs could keep affected limbs abduction. From postoperative 1 day, they exercised in an order of active aid→active→anti-resistance. Patients received prosthetic replacement were rechecked at
6 weeks postoperation and began weight-bearing activities with the aid of crutches, internal fixation patients were rechecked the photos at 8-12 weeks and began weight-bearing activities with crutches.
Anti-osteoporosis treatment after surgery
Vitamin D + calcium or Caltrate orally, a tablet per time, twice a day; salmon calcitonin 50 IU, subcutaneous injection, once a day; risedronate 5 mg daily between two meals, for 3 months.
Main outcome measures
Modified Harris hip function score was to evaluate treatment effects, including pain, function, deformity, activity[3]: Total score was 100 points, 90-100 was excellent, 80-89 was good, 70-79 was fair, below 70 was poor.
Statistical analysis
Using SPSS 13.0 software, measurement data were expressed as mean ± SD. Intergroup comparison was done using t test. A level of P < 0.05 was considered statistically significant.