中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (29): 5425-5428.doi: 10.3969/j.issn.1673-8225.2011.29.026

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

急性骨损伤生物修复材料的选择与表面修饰

梁华伟   

  1. 河南理工大学体育学院体质健康中心，河南省焦作市  454000
  • 收稿日期:2011-01-20 修回日期:2011-04-24 出版日期:2011-07-16 发布日期:2011-07-16
  • 作者简介:梁华伟★，男，1978年生，河南省焦作市人，汉族，2008年北京体育大学毕业，硕士，讲师，主要从事运动训练与体育保健的研究。 beijing1975@126.com

Biomaterial selection and surface modification for repair of acute bone injuries

Liang Hua-wei   

  1. Center of Physical Health, College of Physical Education, Henan Polytechnic University, Jiaozuo  454000, Henan Province, China
  • Received:2011-01-20 Revised:2011-04-24 Online:2011-07-16 Published:2011-07-16
  • About author:Liang Hua-wei★, Master, Lecturer, Center of Physical Health, College of Physical Education, Henan Polytechnic University, Jiaozuo 454000, Henan Province, China beijing1975@126.com

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被引次数

1

摘要：

背景：对于严重或较为复杂的急性骨损伤的修复，选择理想骨基质材料为细胞提供理想的生存环境。
目的：综述骨组织工程基质材料的运用和对其进行改性、修饰的相关研究成果。
方法：应用计算机检索CNKI和PubMed数据库中1999-01/2011-03关于软骨损伤及医用缝线材料的文章，在标题和摘要中以“骨，材料，修饰”或“bone，materials，modified”为检索词进行检索。选择文章内容与缝线材料相关，同一领域文献则选择近期发表或发表在权威杂志文章。初检得到237篇文献，根据纳入标准选择28篇文章进行综述。
结果与结论：理想骨基质材料的选择，必须要具有良好的生物相容性、相应的硬度，并可为细胞吸附、再生和繁殖的理想环境，从目前对骨基质材料的运用情况来看，各种材料在实践运用中，利弊犹存。所以，为了使基质材料尽量达到理想效果，选择理想的基质材料尤为关键，同时对其进行必要的改性或表面修饰处理，以适应理想基质材料的需要，也是尤为重要。

关键词: 骨, 材料, 修饰, 综述文献

Abstract:

BACKGROUND: For the repair of severe or complicated acute bone injury, the ideal choice of bone matrix materials provides an ideal living environment for the cells.
OBJECTIVE: To review the application and surface modification of bone tissue engineering matrix materials.
METHODS: A computer search of CNKI and PubMed (1999-01/2011-03) was performed to find articles addressing cartilage injury and medical suture materials using the keywords of “bone, materials, modified” in Chinese and English. Articles published in the recent or in authorized journals were preferred. Finally, 28 of 237 articles were included.
RESULTS AND CONCLUSION: Ideal bone matrix materials must have good biocompatibility, appropriate hardness, and can provide an ideal environment for cell adsorption, regeneration and reproduction. The advantages and disadvantages in the use of various bone matrix materials still exist. Therefore, in order to achieve the desired result of the matrix material, to select the desired matrix material is particularly critical, and necessary surface modification is required to meet the ideal matrix material needs.

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