中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (20): 3719-3722.doi: 10.3969/j.issn.1673-8225.2011.20.026

• 组织构建与中医药 tissue construction and traditional Chinese medicine • 上一篇    下一篇

八角茴香提取液的抗疲劳效应

何敬和1，姚  丽2，常  震1   

  1. 武警医学院，1军体教研室，2生物化学教研室，天津市  300162
  • 收稿日期:2010-11-09 修回日期:2010-12-07 出版日期:2011-05-14 发布日期:2011-05-14
  • 通讯作者: 姚丽，硕士，讲师，武警医学院生物化学教研室，天津市 300162 Yaoli-003@163. com
  • 作者简介:何敬和★，男，1975年生，山东省济宁市人，汉族，2006年四川大学毕业，硕士，讲师，主要从事军人体能与健康促进方面的研究。 xk-003@163. com
  • 基金资助:

    武警医学院面上课题资助项目(WYM201023)。

Anti-fatigue effects of Fructus Anisi Stellati extract

He Jing-he1, Yao Li2, Chang Zhen1   

  1. 1Department of Military Sports, 2Department of Biochemistry, Medical College of Chinese People’s Armed Police Force, Tianjin  300162, China
  • Received:2010-11-09 Revised:2010-12-07 Online:2011-05-14 Published:2011-05-14
  • Contact: Yao Li, Master, Lecturer, Department of Biochemistry, Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China Yaoli-003@163.com
  • About author:He Jing-he★, Master, Lecturer, Department of Military Sports, Medical College of Chinese People’s Armed Police Force, Tianjin 300162, China xk-003@163.com
  • Supported by:

    the General Subject of Medical College of Chinese People’s Armed Police Force, No. WYM201023*

PDF

514

被引次数

8

摘要：

背景：延缓疲劳或消除疲劳是运动医学的研究热点，利用中药来消除运动性疲劳，提高机体运动能力，具有重要应用前景。
目的：观察八角茴香提取液对小鼠的抗疲劳作用。
方法：将120只雄性昆明种小鼠按体质量随机分为4组：分别给予21，42，84 mL/(kg•d)的八角茴香提取液和蒸馏水， 35 d后，检测小鼠力竭游泳时间、爬杆时间及运动后血乳酸水平；40 d后，检测小鼠运动后肝糖原含量、血清尿素氮和乳酸脱氢酶活力。
结果与结论：八角茴香提取液可增加小鼠力竭游泳时间、爬杆时间及运动后肝糖原含量，提高运动后小鼠血乳酸脱氢酶活力，同时降低小鼠运动后血乳酸及尿素氮水平，尤以84 mL/(kg•d)八角茴香提取液的效果最明显(P < 0.05或P < 0.01)。说明八角茴香提取液有明显的抗疲劳作用。

关键词: 八角茴香提取液, 抗疲劳, 抗氧化, 物质代谢, 有氧代谢, 中枢性疲劳

Abstract:

BACKGROUND: Delay fatigue or fatigue elimination are the research focuses in the sports medicine. It has great prospect to utilize traditional Chinese drug to eliminate sports fatigue and increase sports ability.
OBJECTIVE: To study the antifatigue effects of Fructus Anisi Stellati on mice.
METHODS: Based on body weight, 120 male Kunming mice were randomly divided into 4 groups, which given 21, 42, 84 mL/  (kg •d) Fructus Anisi Stellati extract or distilled water. Exhaustive swimming time, pole-climbing time and post exercise lactate level were detected at 35 days after medication. Post exercise hepatic glycogen content, serum urea nitrogen and lactate dehydrogenase activity were determined at 40 days after medication. 
RESULTS AND CONCLUSION: The Fructus Anisi Stellati could increase exhaustive swimming time, pole-climbing time and post exercise hepatic glycogen content, raise lactate dehydrogenase activity, decline lactate and serum urea nitrogen levels, the effectiveness was most manifest in the 84 mL/(kg•d) group (P < 0.05 or P < 0.01). The findings demonstrated that Fructus Anisi Stellati has noticeable antifatigue effect on mice.

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