关键词: 骨填充材料, 骨肿瘤, 骨缺损, 同种异体骨, 生物材料

Abstract:

BACKGROUND: Bone filling materials have good bioactivity, biocompatibility, biological safety and mechanical properties, and can induce formation of new bones to realize a self-repair of bones. This kind of material is an efficient, safe, cost-effective bone substitute, and can be used as repair materials for bone defects following repair of benign cystic lesions and tumor-like lesions.
OBJECTIVE: To summarize the progress in bone filling materials for bone defects following bone tumor resection.
METHODS: A computer-based search of VIP databases from January 1998 to October 2009 was performed using “bone filling materials, bone tumor, bone defect” as keywords to retrieve relevant articles about bone filling materials for bone defects after bone tumor resection. There were 22 articles involved in result analysis.
RESULTS AND CONCLUSION: Allogeneic bone and autologous bone compound is a high-effective methods for bone defects after bone tumor segment resection in clinic. Allogeneic bone as a permanent implant material for bone reconstruction can be completely absorbed by the host, and has great advantages relevant to other materials. It is a implant material with high clinical value for bone defects due to benign tumor resection of the extremities, especially for large bone defects.