中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (35): 6471-6474.doi: 10.3969/j.issn.1673-8225.2010.35.003

• 数字化骨科 digital orthopedics • 上一篇    下一篇

计算机辅助设计与钛合金精密铸造的颅骨缺损个体化修复体

夏德林，周航宇，付光新，陈俊良，马  征   

  1. 四川省泸州医学院附属口腔医院口腔颌面外科，四川省泸州市 646000
  • 出版日期:2010-08-27 发布日期:2010-08-27
  • 作者简介:夏德林☆，男，1972年生，四川省资阳市人，汉族，2004年中国协和医科大学毕业，博士，副教授，主要从事颅颌面整形与修复重建研究。 xiadeln@163.com
  • 基金资助:

    四川省科技厅应用基础研究项目资助。

Computer aided design and exact foundry of individualized titanium-alloy implant for reconstruction of cranial defects

Xia De-lin, Zhou Hang-yu, Fu Guang-xin, Chen Jun-liang, Ma Zheng   

  1. Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Luzhou Medical College, Luzhou  646000, Sichuan Province, China
  • Online:2010-08-27 Published:2010-08-27
  • About author:Xia De-lin☆, Doctor, Associate professor, Department of Oral and Maxillofacial Surgery, Affiliated Stomatology Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China xiadeln@163.com
  • Supported by:

    the Applied Basic Research Program of Sichuan Provincial Science and Technology Bureau*

PDF

407

被引次数

7

摘要：

背景：现代的颅骨成形不应仅停留在修补缺损恢复颅腔完整性的基础上，而应达到颅骨表面解剖重建，兼顾形态和功能。目前常规使用的颅骨缺损修复方法存在许多缺限与不足，特别在修复巨大、复杂部位的缺损更加困难。
目的：探讨利用CT数据、CAD、快速成型技术结合现代铸造工艺，以医用钛合金为材料颅骨缺损个体化修复体原位辅助设计与精密铸造的方法。
方法：以成年山羊为实验对象，建立颅骨缺损的动物模型，CT连续薄层容积扫面获取原始数据，经数据处理后三维建模，在surfacer9.0中运用原位完全贴合、交互式屏幕显示法设计修复体三维模型。将设计的个性化修复体三维曲面模型数据输入快速成型机，完成修复体的原型制造。以钛合金为材料，运用熔模铸造法制作个体化修复体。
结果与结论：通过CT原始数据的获取、图像处理三维重建、原位完全贴合法个体化计算机辅助设计、修复体快速原型制造、钛合金精密铸造成型过程完成个体化修复体制作。修复体与缺损具有极强的适配性，吻合良好。结果说明基于CT数据、计算机辅助设计、快速成型技术为解决临床医学中长期困扰的“量身定作”问题提供了有效的方法和制作手段，简化了手术操作，缩短了手术时间，降低了手术风险，外形功能恢复满意。

关键词: 计算机辅助设计, 快速成型, 颅骨缺损, 颅骨成形, 钛合金, 数字化骨科

Abstract:

BACKGROUND: Modern cranioplasty should consider appearance and function, recovering integrity of the cranial cavity, and reconstruction of surface anatomy of cranial vault. Conventional methods exist many disadvantaged, especially in reconstructing huge and complex defect of craniofacial areas.
OBJECTIVE: To explore the method of prefabricated and individualized implant for reconstruction of cranial defect by the techniques of CT data, computer imaging processing, rapid prototyping and exact foundry of titanium.
METHODS: The animal model of cranial defect was established by the adult goat. The raw data was obtained from continuous thin-layer volume computer tomography scanning. Three-dimensional curved model of implant was designed by in situ fully fit and interactive screen method through a serial disposal of CT imaging. The data of three-dimensional curved model was transmitted to rapid prototyping machine, the prototyping was finished. The individualized implant was prefabricated by exact foundry of titanium alloy.
RESULTS AND CONCLUSION: The prefabricated individualized cranial implant was finished by a series of CT data processing, computer aided designing, rapid prototyping and titanium casting. The implant is well fitting with defect area. The results showed that the technique that prefabricated and individualized implant basing on CT data, computer aided design and rapid prototyping provides an effective method for reconstruction of cranial defect and resolves clinical difficulty of custom-made implant for patient. Moreover, this method has advantages of reduced operation time, simple operation-step, high accuracy of their fitting and satisfied function and aesthetic result restoring.

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