中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (12): 2233-2236.doi: 10.3969/j.issn.1673-8225.2010.12.036

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

人工生物材料在肌腱损伤中的应用

宋清华   

  1. 河南理工大学体育学院体质健康中心,河南省焦作市  454000
  • 出版日期:2010-03-19 发布日期:2010-03-19
  • 作者简介:宋清华★,男,1976年生,河南省周口市人,汉族,2008年北京体育大学毕业,硕士,讲师(中心主任),主要从事运动训练与体育康复保健学的研究。 sqh@hpu.edu.cn

Application of artificial biomaterials to tendon injury

Song Qing-hua   

  1. Constitution Health Center, College of Physical Education, Henan Polytechnic University, Jiaozuo   454000, Henan Province, China
  • Online:2010-03-19 Published:2010-03-19
  • About author:Song Qing-hua★, Master, Lecturer, Constitution Health Center, College of Physical Education, Henan Polytechnic University, Jiaozuo 454000, Henan Province, China sqh@hpu.edu.cn

摘要:

背景:体育运动训练中肌腱损伤较为常见,肌腱损伤后由于腱鞘的完整性遭到破坏,其愈合周期较长甚至很难康复,随着组织工程学治疗技术应用于运动医学领域,运用人工生物材料干预肌腱损伤后的愈合与康复手段也日趋多样与成熟。
目的:对人工材料干预肌腱康复与治疗的手段进行分类与归纳,对肌腱损伤后人工生物材料干预下的康复与治疗手段及机制进行探讨。
方法:应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)及CNKI数据库(www.cnki.net/index.htm),在标题和摘要中以“生物材料,肌腱”或“biological material,tendon”为检索词进行检索。选择文章内容与肌腱治疗手段、材料学特点、生物相容性及其应用效果相关,同一领域文献则选择近期发表或发表在权威杂志文章,最终纳入34篇文献。
结果与结论:腱鞘是防止肌腱粘连的重要屏障,肌腱损伤后,尤其损伤较为严重时腱鞘的完整性遭到破坏,临床上腱鞘损伤后很难再原位缝合。因此,肌腱损伤后在愈合过程中,如何避免其粘连的形成,是解决肌腱损伤后修复的一个关键问题。现代人工生物材料的妥善运用,为肌腱损伤后的快速良好康复提供了可能及保障。

关键词: 生物材料, 肌腱, 康复, 运用, 人工生物材料

Abstract:

BACKGROUND:Tendon injury commonly occurred during athletic sports. Following tendon injury, the entire tendon sheath was destructed, whose healing cycle was long, even difficult to recover. With the application of tissue engineering treatment technique, to athletic medicine, artificial biomaterial in intervening tendon injury healing and rehabilitation maneuver has become various and mature.
OBJECTIVE: To classify and summarize artificial materials in intervening tendon rehabilitation and treatment methods, and to explore rehabilitation, treatment methods and mechanism of artificial biomaterial intervention following tendon injury.
METHODS: A computer-based online search was performed on PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI (www.cnki.net/index.htm). In the titles and abstracts, the key words included “biomaterial”, and “tendon”. Articles addressing tendon treatment methods, material properties, biocompatibility and its application effects were included, and those in the same field that published recently or in authoritative journals. Finally, 34 articles were included.
RESULTS AND CONCLUSION: The tendon sheath is the important barrier to prevent tendon adhesion. Following tendon injury, especially severe injury, the entire tendon sheath is destructed. In clinic, the tendon sheath following injury is difficult to be sutured. Therefore, how to avoid adhesion form is a key to solve repair following injury during the healing of tendon. The perfect application of modern artificial biomaterials provides possibility and insurance for rapid good rehabilitation following tendon injury.

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