Chinese Journal of Tissue Engineering Research ›› 2010, Vol. 14 ›› Issue (8): 1488-1490.doi: 10.3969/j.issn.1673-8225.2010.08.038

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Breast malignant tumor following polyacrylamide hydrogel injection: Two cases report

Wang Mu1, Wang Xiao-yang2, Hou Xiao-dong1, Rong Rong1, Zhou Zhi-gang1, Li Xiang3, Ouyang Xue3   

  1. 1 Department of Plastic and Aesthetic Surgery, 3 Department of Pathology, Shanghai Chinese People’s Armed Police Force Hospital, Shanghai  201103, China; 2 Shanghai Beverly Hills Medical Cosmetic Clinic, Shanghai  200002, China
  • Online:2010-02-19 Published:2010-02-19
  • Contact: Zhou Zhi-gang, Associate chief physician, Department of Plastic and Aesthetic Surgery, Shanghai Chinese People's Armed Police Force Hospital, Shanghai 201103, China zg918@yahoo.com.cn
  • About author:Wang Mu★, Master, Department of Plastic and Aesthetic Surgery, Shanghai Chinese People's Armed Police Force Hospital, Shanghai 201103, China wm122588@hotmail.com

Abstract:

BACKGROUND: Breast augmentation with polyacrylamide hydrogel injection has been used nearly for a decade in some Chinese medical therapy units. More patients need to be removing injections or a second augmentation due to complications. More attention should be paid for possibility of complications concomitant with breast malignant tumor.
OBJECTIVE: Two cases of breast invasive duct carcinoma diagnosed after removing injection were analyzed retrospectively in order to increase the importance of detection rate of breast malignant tumor.
METHODS: Two cases in all 41 assembled patients which were removed polyacrylamide hydrogel injections from 82 breasts were diagnosed with invasive carcinoma. The characteristics of medical history, physical diagnosis, image diagnosis and pathological examination were analyzed retrospectively.
RESULTS AND CONCLUSION: The detection rate of breast malignant tumor should arise more attention in patients requiring removal of polyacrylamide hydrogel injection. The following aspects should be emphasized such as the comprehensive analysis for the results of physical diagnosis and image diagnosis, tumor-free operation with more samples from suspicious nodules and frozen pathological examination. The principles of cancer surgery should be followed in pathological diagnosed cases in case of iatrogenic metastasis and spread of breast malignant tumor.

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