Chinese Journal of Tissue Engineering Research ›› 2019, Vol. 23 ›› Issue (8): 1258-1264.doi: 10.3969/j.issn.2095-4344.1088

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Effectiveness and safety of knotless barbed suture for primary total knee or hip arthroplasty: a meta-analysis  

Zhang Zhiliang1, Han Pengfei1, Ren Guangzong1, Chen Chenglong1, Li Pengcui2, Wei Xiaochun2   

  1. 1Second Medical School of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China; 2Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Online:2019-03-18 Published:2019-03-18
  • Contact: Wei Xiaochun, MD, Professor, Doctoral supervisor, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • About author:Zhang Zhiliang, Master candidate, Second Medical School of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Supported by:

    the National International Science and Technology Cooperation Project, No. 2015DFA33050 (to WXC); the National Natural Science Foundation for the Youth, No. 81601949 (to LPC); the Overseas Returnee Research Project of Shanxi Province, No. 2016-118 (to LPC)

Abstract:

BACKGROUND: Knotless barbed suture is an absorbable surgical suture with two-way barbs that enables continuous suture wounds. Compared with traditional knotted sutures, knotless barbed suture has the advantages of shortening suture time, promoting wound healing and reducing infection. It has been widely used in urology, obstetrics and gynecology, but its application in the field of total knee or hip arthroplasty is still controversial.

OBJECTIVE: To systematically assess the effectiveness and safety of knotless barbed suture for primary total knee or hip arthroplasty by meta-analysis.
METHODS: Randomized controlled trials addressing knotless barbed suture versus traditional knotted sutures for total joint arthroplasty were retrieved from Embase, PubMed, Web of Science, WanFang, CNKI, CBM, WanFang and VIP databases before September 2018. The articles were screened according to the inclusion and exclusion criteria. After quality assessment and data extraction, meta-analysis was performed on Revman 5.3 software.
RESULTS AND CONCLUSION: (1) Eight randomized controlled trails were included, with 476 cases for trial group (knotless barbed suture) and 498 cases for control group (traditional knotted sutures). (2) Meta-analysis results revealed that the trail group had the shorter operation time [MD=-6.96, 95%CI (-10.60, -3.31), P < 0.001], lower incidence of infection [RR=0.31, 95%CI (0.14, 0.69), P=0.004] and higher American Knee Society scores at postoperative 3 months [MD=-2.04, 95%CI (-3.92, -0.15), P=0.03]. There was no significant difference between two groups in the incision related complications [RR=0.76, 95%CI (0.36, 1.62), P=0.48], American Knee Society scores at postoperative 6 weeks [MD=-0.22, 95%CI (-3.10, 2.66), P=0.88], range of motion within postoperative 6 weeks [MD=-0.74, 95%CI (-4.19, 2.71), P=0.67] and range of motion after 3 months postoperatively [MD=-1.14, 95%CI (-6.10, 3.82), P=0.65]. (3) To conclude, knotless barbed suture applied in primary total knee or hip arthroplasty does not increase the incidence of incision-related complications, but can shorten the operation time, prevent infection and promote knee function recovery, and it is a safe and effective new material for suturing the incision.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Arthroplasty, Replacement, Randomized Controlled Trial, Meta-Analysis, Tissue Engineering

CLC Number: