中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (34): 6355-6358.doi: 10.3969/j.issn.1673-8225.2010.34.020

• 药物控释材料 drug delivery materials • 上一篇    下一篇

藻酸盐敷料应用于难愈性烧伤创面随机对照

黄国宝，张  磊，张科验，周  玲，吴秋合，宋国栋   

  1. 山东大学附属济南市中心医院烧伤科，山东省济南市  250013
  • 出版日期:2010-08-20 发布日期:2010-08-20
  • 通讯作者: 张磊，硕士，主治医师，山东大学附属济南市中心医院烧伤科，山东省济南市 250013 Chenwen1816@163.com
  • 作者简介:黄国宝★，男，1979年生，山东省青州市人，汉族，2004年山东大学医学院毕业，硕士，主治医师，主要从事烧伤创面修复研究。 huangguobao@163.com

Therapeutic effects of alginate dressing for refractory burn wound: A randomized controlled study

Huang Guo-bao, Zhang Lei, Zhang Ke-yan, Zhou Ling, Wu Qiu-he, Song Guo-dong   

  1. Department of Burn, Jinan Central Hospital Affiliated to Shandong University, Jinan   250013, Shandong Province, China
  • Online:2010-08-20 Published:2010-08-20
  • Contact: Zhang Lei, Master, Attending physician, Department of Burn, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, Shandong Province, China Chenwen1816@163.com
  • About author:Huang Guo-bao★, Master, Attending physician, Department of Burn, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, Shandong Province, China huangguobao@163.com

PDF

779

被引次数

57

摘要：

背景：研究发现藻酸盐敷料可有效促进创面愈合，但对于烧伤难愈创面的研究尚须进一步开展。
目的：观察藻酸盐敷料应用于烧伤患者难愈创面的临床效果。
方法：60例患者随机分为常规换药组和藻酸盐敷料组，每组30例，两组患者年龄、性别、创面面积及全身状况等因素的差别均无显著性意义。常规换药组用凡士林纱布覆盖创面，藻酸盐敷料组用藻酸盐敷料覆盖创面。每两三天换药1次，直到创面愈合。对比观察两组创面愈合时间及愈合率、局部炎症反应和皮片排斥反应、创面愈合方式，创面愈合后皮肤质量情况。
结果与结论：藻酸盐敷料较凡士林油纱可明显缩短创面愈合时间，提高创面愈合率，减轻局部炎症反应，创面愈合后皮肤质量明显提高。与常规换药相比，应用藻酸盐敷料可明显减少难愈性创面愈合时间，可作为难愈性创面的治疗方法之一。

关键词: 藻酸盐, 烧伤, 难愈创面, 创面愈合, 敷料

Abstract:

BACKGROUND: Studies have found that alginate dressing can accelerate wound healing, but the effects of treating refractory burn wound deserve further research.
OBJECTIVE: To observe the clinical therapeutic effects of alginate dressing on treating refractory burn wound.
METHODS: Sixty patients with refractory burn wound were randomly divided into control group with vaseline gauze and treatment group with alginate dressing. There were no significant differences in patient’s age, gender, wound area and general conditions. The wound was changed dressing every 2-3 days, until the wound healed. The healing period and healing rate, infection state, free skin graft, healing methods and healing quality of the patients in the two groups were observed and compared.
RESULTS AND CONCLUSION: The alginate dressing can shorten wound healing time, accelerate wound healing, decrease the wound infection and improve the healing quality. Compared with routine therapy, the alginate dressing dramatically reduce the wound healing time, can be used as one of the modalities for refractory burn wound.

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