中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (21): 3843-3846.doi: 10.3969/j.issn.1673-8225.2010.21.010

• 材料力学及表面改性 material mechanics and surface modification • 上一篇    下一篇

不同种类人工晶状体在眼内位移产生的人工晶状体眼调节变化

南  莉1, 汤  欣1, 刘永基2, 李丽华1   

  1. 1天津医科大学眼科临床学院, 天津市眼科医院,天津市眼科学与视觉科学重点实验室, 天津市 300020;2天津市南开大学现代光学研究所,天津市 300071
  • 出版日期:2010-05-21 发布日期:2010-05-21
  • 通讯作者: 汤 欣,博士,博士生导师,主任医师,天津医科大学眼科临床学院,天津市眼科医院,天津市眼科学与视觉科学重点实验室,天津市 300020 tangprof@yahoo.com.cn
  • 作者简介:南 莉☆,女,1973年生,天津市人,汉族,天津医科大学眼科学在读博士,主治医师,主要从事视光学临床和研究。 nanli73@yahoo.com
  • 基金资助:

    天津市卫生局科技基金攻关资助项目。

Changes of pseudophakic accommodation produced by different types of intraocular lenses movement

Nan Li1, Tang Xin1, Liu Yong-ji2, Li Li-hua1   

  1. 1 Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin  300020, China; 2 Institute of Modern Optics, Nankai University, Tianjin  300071, China
  • Online:2010-05-21 Published:2010-05-21
  • Contact: Tang Xin, Doctor, Doctoral supervisor, Chief physician, Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China tangprof@yahoo.com.cn
  • About author:Nan Li☆, Studying for doctorate, Attending physician, Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, China nanli73@yahoo.com
  • Supported by:

    the Science and Technology Tackle Program of Health Bureau of Tianjin

摘要:

背景:不同种类人工晶状体的材料和光学设计影响其光学特性,临床数据难以分析不同人工晶状体在眼内位移产生的人工晶状体眼调节。
目的:观察不同人工晶状体种类在眼内位移过程中产生的人工晶状体眼调节变化。
方法:在Zemax光学设计中构建Liou-Brennan眼模型,分别用材料和设计不同的不同种类人工晶状体替换自然晶状体,采用光线追迹原理计算人工晶状体前移产生的人工晶状体眼调节。
结果与结论:随着人工晶状体前移距离增加,人工晶状体眼调节增加。丙烯酸和聚甲基丙烯酸甲酯人工晶状体前移产生的调节接近;凸平型和等双凸型设计人工晶状体前移产生的调节差别不显著;球面人工晶状体前移产生的调节略大于非球面人工晶状体。结果说明人工晶状体在眼内的位移引起焦点偏移,提供了一定调节,与人工晶状体眼的高阶像差、角膜的近视性散光和多焦性等因素共同构成人工晶状体眼的表观调节。人工晶状体种类对人工晶状体眼调节影响不显著。

关键词: 人工晶状体, 材料, 设计, 非球面性, 调节, 生物材料

Abstract:

BACKGROUND: Intraocular lens (IOL) made from different materials and optical designs have different optical characteristics. It is hard to clinically analyze the amount of pseudophakic accommodation caused by IOL movement inside of the eye.  
OBJECTIVE: To study pseudophakic accommodation induced by intraocular movement of different types of intraocular lenses.
METHODS: By using Zemax optical design program, the Liou-Brennan eye model implanted with different types of IOL was constructed. Ray-tracing method was adopted to calculate pseudophakic accommodation induced by IOL forward movements.
RESULTS AND CONCLUSION: The pseudophakic accommodation was increased with IOL forward movement. IOL made from acrylic and polymethylmethacrylate induced similar rate of pseudophakic accommodation. It was not significantly different between IOL with optical design of convex-plano and equal-convex as well. Slight higher pseudophakic accommodation caused by spherical IOL forward movement than aspheric IOL. The type of IOLs did not have significant effect on pseudophakic accommodation.

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