中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (30): 5614-5617.doi: 10.3969/j.issn.1673-8225.2010.30.025

• 数字化骨科 digital orthopedics • 上一篇    下一篇

生物组织传热红外热成像的三维温度场重建

马国军1 ,2,江国泰1,孙  兵1   

  1. 1 同济大学生命科学与技术学院,上海市  200092;  2 江苏科技大学电子信息学院, 江苏省镇江市  212003
  • 出版日期:2010-07-23 发布日期:2010-07-23
  • 通讯作者: 江国泰,教授,博士生导师,同济大学生命科学与技术学院,上海市 200092
  • 作者简介:马国军☆,男,1976年生,江苏省丹阳市人,汉族,同济大学在读博士,讲师,主要从事生物医学信号处理研究。 kitty_171200@yahoo.com.cn
  • 基金资助:

    国家自然科学基金项目(50977064),课题名称:脉冲变频电磁场的生物热效应及其对乳腺癌细胞杀伤作用。

Infrared thermography based 3D temperature field reconstruction of biological tissue heat transfer

Ma Guo-jun 1,2, Jiang Guo-tai1, Sun Bing1   

  1. 1 School of Life Sciences and Technology, Tongji University, Shanghai  200092, China
    2 School of Electronics and Information, Jiangsu University of Science and Technology, Zhenjiang  212003, Jiangsu Province, China
  • Online:2010-07-23 Published:2010-07-23
  • Contact: Jiang Guo-tai, Professor, Doctoral supervisor, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China
  • About author:Ma Guo-jun☆, Studying for doctorate, Lecturer, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; School of Electronics and Information, Jiangsu University of Science and Technology, Zhenjiang 212003, Jiangsu Province, China kitty_171200@yahoo.com.cn
  • Supported by:

    the National Natural Science Foundation of China, No. 50977064*

摘要:

背景:红外热成像技术作为新型的非接触测温方法,具有无损、快捷、方便的特点,并且可以利用计算机技术对生物组织内部温度场进行三维重构。
目的:针对肿瘤热疗过程中温度场测量与重构,提出生物组织温度场三维重建新方法。
方法:首先根据生物传热和红外热辐射信息,采用红外热成像技术非接触测量分层体模的二维温度分布信息;然后,将此温度信息转换为人眼可视的灰度图,并进行伪彩色处理,同时,利用传输函数为热像图序列的每一个像素重新分配颜色和不透明度,从而对分层体模的温度场利用体绘制光线投射算法进行三维重建。
结果与结论:实验结果表明,依据红外热辐射的原理,采用红外热像仪接受红外信息并将其转换为温度值,然后采用伪彩色显示方法,对分层体模的三维温度场进行光线投射重建,为热疗过程中生物组织内部三维温度场的测量、观测提供了新的技术手段与方法。

关键词: 生物传热, Pennes方程, 温度场, 三维重建, 数字化医学

Abstract:

BACKGROUND: Infrared thermography as a new technology for non-contact temperature measurement has the advantage of non-invasive, fast and convenient. And computer can be used to reconstruct 3D inner temperature field of biological tissue.
OBJECTIVE: For measurement and reconstruction of temperature field in tumor hyperthermia, to propose new methods of 3D temperature field reconstruction for biological tissue.
METHODS: Infrared thermography technology was applied to measure 2D temperature distribution non-contactly of sliced-biomaterial, which based on bi-heat transfer and information of infrared thermal emitter. Temperature information was converted to gray images to be visualized, and pseudo-colorly processed. In addition, every pixel in infrared thermograph was allocated color and opacity by transfer function, so as to reconstruct temperature field of sliced-biomaterial by volume rendering ray casting algorithm.
RESULTS AND CONCLUSION: Experiment results showed that, based on algorithm of infrared thermal emitter and information obtained from thermal infrared imager was converted to temperature and displayed as pseudo-color. And 3D temperature field obtained from sliced-biomaterial was reconstructed with ray casting. It provides new technology and method for measurement and observation of temperature field in hyperthermia.

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