Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (26): 4212-4218.doi: 10.3969/j.issn.2095-4344.2014.26.021
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Peng Xiao-zhong, Xiao Kan-kan
Online:2014-06-25
Published:2014-06-25
Contact:
Xiao Kan-kan, Studying for doctorate, Physician, Department of Spine Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China
About author:Peng Xiao-zhong, Associate chief physician, Department of Spine Surgery, Liuzhou Worker’s Hospital, Liuzhou 545005, Guangxi Zhuang Autonomous Region, China
CLC Number:
Peng Xiao-zhong, Xiao Kan-kan . Minimally invasive versus open pedicle screw fixation for repair of thoracolumbar fractures[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(26): 4212-4218.
2.1 参与者数量分析 按意向性分析,纳入94例单节段无神经症状胸腰椎骨折患者,分为3组,全部进入结果分析,无脱落。所有患者随访6个月。 2.2 基线资料比较 3组患者例数相仿,开放内固定组34例,Quadrant通道内固定组30例,Sextant内固定组30例。受伤平均年龄超过40岁,男性(57例)多于女性(37例)。受伤最多部位在T12(41例)和L1(40例),L2及L3较少,分别为10例和3例。骨折主要为A3型骨折,即爆散型骨折,达64例;其他骨折类型A1型11例,A2型13例,B1型6例。 3组患者内固定前一般资料,包括年龄、性别、损伤节段、骨折类型比较,差异无显著性意义(P > 0.05,表1)。"
2.3 围手术期结果比较 3组手术方式的切口长度均数,开放内固定组最长,Quadrant通道内固定组次之,Sextant内固定组最短。平均手术时间,开放内固定组手术时间最长。术中出血量Sextant内固定组最少。在这3组病例中,没有进行输血治疗。术中X射线暴露时间最短为开放内固定组,Sextant内固定组最长。在平均住院时间方面,Sextant内固定组最短,开放内固定组最长。平均下地时间,Sextant内固定组最短。 微创与开放内固定组围手术期指标比较,Quadrant通道内固定组、Sextant内固定组在切口长度、术中出血量、手术时间、住院时间、平均下地时间方面均显著优于开放内固定组(P < 0.05,表2)。"
2.5 临床疗效结果比较 内固定后6个月全部患者均有恢复,胸腰部疼痛目测类比评分、Oswestry功能障碍指数均下降。临床疗效指标比较,内固定后6个月胸腰部疼痛目测类比评分、Oswestry功能障碍指数较内固定前有明显改善,差异有显著性意义(P < 0.05)。内固定后6个月,Quadrant通道内固定组、Sextant内固定组与开放性内固定组比较,差异有显著性意义(P < 0.05,表6,7)。 2.6 两微创组之间指标比较 Quadrant通道内固定组与Sextant内固定组围手术期指标比较:与Quadrant通道内固定组比较,Sextant内固定组在切口长度、术中出血量、平均下地时间方面有明显优势(P < 0.05,见表2)。 Quadrant通道内固定组与Sextant内固定组目测类比评分及Oswestry功能障碍指数比较:对于目测类比评分及Oswestry功能障碍指数,两组间内固定前差异无显著性意义(P > 0.05);而内固定后6个月比较,Sextant内固定组较Quadrant通道内固定组有明显优势(P < 0.05,见表6,7)。 2.7 不良事件 所有病例未出现脊髓、神经根、血管或者脏器损伤的情况。内固定后3 d复查CT椎弓根位置,开放内固定组螺钉破椎弓根壁约2例,Quadrant通道内固定组破椎弓根内侧壁1例,Sextant内固定组破椎弓根外侧壁1例。 "
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