Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (38): 7207-7210.doi: 10.3969/j.issn.2095-4344.2012.38.033

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Intra-articular radioisotope of 32P-colloidal chromic phosphate for knee joint synovitis: A follow-up of 28 cases

Zhu Yue, Zhao Jin-zhong, Yue Zhi-bin, Teng Yue   

  1. Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
  • Received:2012-01-15 Revised:2012-03-29 Online:2012-09-16 Published:2012-09-16
  • About author:Zhu Yue★, Master, Attending physician, Department of Orthopedics, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China zhuyue999999@ yahoo.com.cn

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Abstract:

BACKGROUND: At present, there are various kinds of nuclides for knee joint synovitis, but their physical characteristics have obvious differences.
OBJECTIVE: To investigate the short-term effect of the intra-articular radioaction of 32P-colloidal chromic phosphate on knee joint synovitis.
METHODS: From January 2008 to December 2009, 28 cases (28 knees) of knee joint synovitis were included and treated with the intra-articular radioisotope of 32P-colloidal chromic phosphate. Their MRI images, active range of motion, Lysholm scores of knee joint before and after treatment were compared.
RESULTS AND CONCLUSION: The period of follow-up was from 14 to 24 months (mean 20.8 months). MRI examination of follow-up showed that synovial hyperplasia was obviously improved in various degrees. Lysholm scores of knee joint were increased from 59.05±11.90 to 80.22±10.16 (P < 0.01); excellent and good rate was 85.7%, as well as active range of motion was increased from (82.78±11.01)° to (107.50°±11.66)° (P < 0.01). Of all the cases, only two cases had no obvious improvement in subjective gall symptoms after treatment, and the rest cases were not found infection, anchylosis, deep venous thrombosis and death of body tissue. These findings suggest that the intra-articular radioisotope of 32P-colloidal chromic phosphate for knee joint synovitis is a safe and effective method.

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