Percutaneous vertebroplasty with low-dose bone cement for acute osteoporotic vertebral compression fractures

doi:10.3969/j.issn.2095-4344.2014.12.002

Abstract

Abstract:

BACKGROUND: Percutaneous vertebroplasty technique has become an effective means for clinical treatment of spinal osteoporotic fractures, but there is the risk of bone cement leakage.
OBJECTIVE: To explore the clinical effect of percutaneous vertebroplasty with low-dose bone cement for acute osteoporotic vertebral compression fractures.
METHODS: From September 2008 to February 2011, 32 patients with osteoporotic compression fractures were treated by percutaneous vertebroplasty. According to the dose of bone cement, the patients were divided into low dose group (2-4 mL) and routine dose group (4-6 mL). In addition, another patients who were hospitalized over the same period for acute osteoporotic compression and could not receive vertebroplasty due to urgical contraindication served as control group.
RESULTS AND CONCLUSION: The pain relief and vertebral height restoration rate of the low dose group and routine dose group were significantly better than the control group (P < 0.05). The bone cement leakage rate and last follow-up incidence of adjacent segment vertebral fractures of the low dose group were also significantly lower than those in the routine dose group (P < 0.05). Vertebroplasty with modified low dose bone cement can achieve satisfactory clinical effects, and effectively reduce the leakage of bone cement and incidence of adjacent segment secondary fractures.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: biocompatible materials, vertebroplasty, osteoporotic fractures, acrylic resins

CLC Number:

R318

Cheng Cai, Wang Lu, Li Shu-kui. Percutaneous vertebroplasty with low-dose bone cement for acute osteoporotic vertebral compression fractures[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(12): 1811-1816.

Figures/Tables 3

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