Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (51): 9549-9552.doi: 10.3969/j.issn.1673-8225.2011.51.012

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Application of a memory alloy elastic metal stent in reconstruction of tracheal defects by pulmonary tissue flaps in dogs

Ji Zi-zhao1, Chen Gang2, Zhang Su-ning1, Shi Wen-jun1   

  1. 1Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang  110004, Liaoning Province, China
    2Department of Cardiothoracic Surgery, First People’s Hospital of Jiujiang, Jiujiang  332000, Jiangxi Province, China
  • Received:2011-08-25 Revised:2011-11-06 Online:2011-12-17 Published:2011-12-17
  • Contact: Shi Wen-jun, Doctoral supervisor, Professor, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China shiwj@cmu2h.com
  • About author:Ji Zi-zhao☆, Doctor, Attending physician, Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China versace_et@ 163.com
  • Supported by:

    Financed Program of Ministry of Health, No. WKZ-2000-1-17*

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Abstract:

BACKGROUND: Lined stent containing good biocompatibility is the key of successful repair of tracheal defect by pulmonary tissue flap. Memory alloy stent is the research hotspot now.
OBJECTIVE: To explore the possibility of autologous pulmonary tissue flap lined with elastic metal stent in replacing tracheal defect.
METHODS: Fourteen hybrid adult dogs came from animal laboratory of Shengjing Hospital of China Medical University were involved. Eight dogs were male and six ones were female with weight of 12-26 kg. The entire trachea of 3 cm or 5 cm was removed in all dogs. Thoracic tracheal reconstruction was performed with autologous pulmonary tissue flap lined with elastic metal stent to replace the tracheal defect.
RESULTS AND CONCLUSION: Four dogs died of the complications and other reasons. Ten dogs survived, and their stomas were good and the barium flux was unobstructed. The replacement of tracheal defect by autologous pulmonary tissue flap lined with elastic metal stent is a possible tracheal reconstruction method.

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