Chinese Journal of Tissue Engineering Research ›› 2011, Vol. 15 ›› Issue (44): 8183-8185.doi: 10.3969/j.issn.1673-8225.2011.44.004

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Diagnosis and treatment of bacterial and fungal pneumonia following liver transplantation

Xu Jian-ji, Zeng Zhong, Duan Jian, Huang Han-fei, Lin Jie, Xu Wang-gang   

  1. Organ Transplantation Center, First Affiliated Hospital of Kunming Medical College, Kunming   650032, Yunan Province, China
  • Received:2011-07-10 Revised:2011-08-06 Online:2011-10-29 Published:2011-10-29
  • Contact: Zeng Zhong, Doctor, Associate professor, Organ Transplantation Center, First Affiliated Hospital of Kunming Medical College, Kunming 650032, Yunan Province, China zzong@medmail. com.cn
  • About author:Xu Jian-ji★, Studying for master’s degree, Organ Transplantation Center, First Affiliated Hospital of Kunming Medical College, Kunming 650032, Yunan Province, China x1417@sina.com
  • Supported by:

    the Natural Science Foundation of Yunnan Province, No. 2007C137M*; Combination Foundation of Science and Technology Department of Yunnan Province, No. 2007C0009F*; Society Development and Science and Technology Plan Foundation of Yunnan Province, No. 2008CA026*

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Abstract:

BACKGROUND: Liver transplant patients prone to lung infections of pathogenic microorganismsdue due to low immunity caused by taking routinei mmunosuppressive drugs.
OBJECTIVE: To retrospectively analyze the diagnosis and treatment of one patient with bacterial combined with fungal pulmonary infection after orthotopic liver transplantation, and summarize the clinical treatment experience.
METHODS: The female patient with hepatic B cirrhosis decompensation was admitted for fever, chilly, cough and dyspnea at 8 months after allogenic orthotopic liver transplantation. CT showed exudation of lobus inferior pulmonis. Cefoperazone /sulbactam sodium was given to eliminate bacterial infection.
RESULTS AND CONCLUSION: After treatment, clinical symptoms were alleviated. One week later, chest CT showed that lobus inferior pulmonis exudation was absorbed compared with pretreatment, but the “ground glass” change of lungs was observed, which suggested fungous infection. Then fluconazole was used. At the end, the patient was cured and discharged.

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