Chinese Journal of Tissue Engineering Research ›› 2012, Vol. 16 ›› Issue (25): 4727-4734.doi: 10.3969/j.issn.1673-8225.2012.25.034

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Biocompatibility of different hemodialysis membrane materials used in renal failure patients: A comparative analysis

Cao Ning   

  1. Department of Blood Purification, the General Hospital of Shenyang Military Region, Shenyang 110016, Liaoning Province, China
  • Received:2012-04-20 Revised:2012-05-10 Online:2012-06-17 Published:2013-11-04
  • About author:Cao Ning☆, M.D., Associate chief physician, Department of Blood Purification, the General Hospital of Shenyang Military Region, Shenyang 110016, Liaoning Province, China cn88860068@ sohu.com

Abstract:

BACKGROUND: Hemodialysis is the main method for the treatment of acute and chronic renal failure; hemodialysis machine can purify the blood through diffusion, convection and filtration procedures by a semi-permeable membrane, and it can excrete the metabolic wastes and excess electrolyte in blood. Selection of the dialysis membrane is closely related with the effectiveness of hemodialysis.
OBJECTIVE: To perform a multilevel analysis on the articles addressing hemodialysis membrane materials using the search and depth analysis capabilities of CNKI database.
METHODS: The CNKI database was used to search articles related to hemodialysis membrane materials from January 2002 to December 2011 with the key words of “hemodialysis, dialysis membrane, biomaterials”. The publishing time, number, subject category, source journals, fund assistance, author distribution, research institution, key words, cited frequency and download frequency of the articles were analyzed. We expressed the articles through text and charts.
RESULTS AND CONCLUSION: A total of 95 articles were included for the analysis. Judging from the number of the articles, there was 20 articles published in 2002; the number of the articles published in Chinese Journal of Blood Purification was up to 19. In view of the key words, hemodialysis membrane was mainly used for the treatment of uremia, and the analysis of the hemodialysis membrane was mainly focused on the biocompatibility of hemodialysis membrane materials, including the effect of dialysis membrane on the oxidative stress and phosphate removal of the patients with maintenance hemodialysis. The articles regarding hemodialysis membrane in CNKI database were analyzed by bibliometric method which could provide the research ideas and valuable data for the workers engaged in the basic research and clinical implementation of hemodialysis membrane materials.

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