Abstract:

BACKGROUND: The effect of total knee arthroplasty for the treatment of hemophilic arthritis is directly related to the coagulation factor replacement treatment programs and surgical techniques.
OBJECTIVE: To summarize the rehabilitation outcome of 12 hemophilic arthritis patients treated with total knee arthroplasty, and to describe the coagulation factor Ⅷ monitoring and alternative treatment program in perioperative period.
METHODS: Take the coagulation factor replacement therapy scheme by Ruijin Hospital as a standard, combining with the actual factor level and experienced surgeon, we operated total knee arthroplasty for the 12 male patients (17 knees) with hemophilic arthritis. Function was assessed using the Cleveland score and the Knee Society Rating Scale.
RESULTS AND CONCLUSION: Results were excellent in 8 knees, fair in 3 knees and poor in 3 knees according to the Cleveland score, 1 thigh amputees and 2 patients who suffered from joint fusion surgery were not involved in this score. According to KSS score, average knee score increased from (23.6±9.0) preoperatively to (86.7±12.1) postoperatively, average knee function score increased from (25.2±28.4) preoperatively to (65.7±39.8) postoperatively. For the patients with hemophilic arthritis, reasonable alternative treatment program can promote the recovery of joint function, but it has bigger risk, so caution is necessary.